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А. К. Мадан

People’s UniversityIN
ORCID0000-0001-5089-1794
h-index
20

via OpenAlex

Citations
1,887

via OpenAlex

Publications
156

About

Dr. Ayush Madan is a researcher and academic professional in the field of Biotechnology with expertise in nanobiotechnology, cytogenetics, cell culture, and toxicological assessment. He earned his Ph.D. in Biotechnology with research focused on the cytotoxic effects of gold and silver nanoparticles on human cells, with special reference to chromosomal aberrations. His work integrates nanoparticle synthesis, characterization, antimicrobial studies, and biomedical applications. He has published more than 100 research papers, review articles, and book chapters. He has also served as editor of more than 50 books with reputed international publishers including Springer, IGI Global, Taylor & Francis, CABI, Cambridge Scholars Publishing, Jenny Stanford Publishing, River Publishers, and Wiley. He has experience in teaching, curriculum development, laboratory establishment, academic administration, and accreditation processes. His research interests include nanotechnology, biotechnology, microbiology, biomedical sciences, and multidisciplinary life science innovations.

Research areas

  • Chemistry
  • Mathematics
  • Biology
  • Computer science
  • Biochemistry

Publications (156)

Sorted by most cited.

  1. Eccentric Connectivity Index:  A Novel Highly Discriminating Topological Descriptor for Structure−Property and Structure−Activity Studies

    1997

    View DOI
    438 cites
  2. Application of Graph Theory: Relationship of Eccentric Connectivity Index and Wiener's Index with Anti-inflammatory Activity

    2002

    View DOI
    172 cites
  3. Eccentric distance sum: A novel graph invariant for predicting biological and physical properties

    2002

    View DOI
    136 cites
  4. Predicting anti-HIV-1 activity of 6-arylbenzonitriles: Computational approach using superaugmented eccentric connectivity topochemical indices

    2007

    View DOI
    82 cites
  5. Predicting anti-HIV activity: computational approach using a novel topological descriptor

    2001

    View DOI
    72 cites
  6. Superpendentic Index:  A Novel Topological Descriptor for Predicting Biological Activity

    1999

    View DOI
    71 cites
  7. Model for Prediction of Anti‐HIV Activity of 2‐Pyridinone Derivatives Using Novel Topological Descriptor

    2006

    View DOI
    54 cites
  8. Immunolocalization of fibroblast growth factor-2 (FGF-2) in the developing root and supporting structures of the murine tooth

    2005

    View DOI
    40 cites
  9. Structure-Activity Study on Antiinflammatory Pyrazole Carboxylic Acid Hydrazide Analogs Using Molecular Connectivity Indices

    1995

    View DOI
    38 cites
  10. Topological models for the prediction of anti-HIV activity of dihydro (alkylthio) (naphthylmethyl) oxopyrimidines

    2004

    View DOI
    36 cites
  11. Predicting anti-HIV activity of phenethylthiazolethiourea (PETT) analogs: computational approach using Wiener's topochemical index

    2004

    View DOI
    36 cites
  12. Structure-Activity Study on Anticonvulsant (Thio) Hydantoins Using Molecular Connectivity Indices

    1994

    View DOI
    29 cites
  13. Topological models for prediction of antihypertensive activity of substituted benzylimidazoles

    2003

    View DOI
    28 cites
  14. Diverse classification models for anti-hepatitis C virus activity of thiourea derivatives

    2014

    View DOI
    27 cites
  15. Classification Models for Safe Drug Molecules

    2012

    View DOI
    24 cites
  16. Topological models for prediction of anti-HIV activity of acylthiocarbamates

    2005

    View DOI
    24 cites
  17. Application of Graph Theory: Prediction of Cytosolic Phospholipase A2 Inhibitory Activity of Propan-2-ones

    2006

    View DOI
    23 cites
  18. Predicting anticonvulsant activity of benzamides/benzylamines: computational approach using topological descriptors

    2002

    View DOI
    23 cites
  19. Relationship of Wiener's index and adjacent eccentric distance sum index with nitroxide free radicals and their precursors as modifiers against oxidative damage

    2003

    View DOI
    21 cites
  20. Applications of graph theory: Relationship of molecular connectivity index and atomic molecular connectivity index with anti-HSV activity

    2001

    View DOI
    21 cites
  21. Expression of fibroblast growth factor‐2 (FGF‐2) in early stages (days 3–11) of the development of the avian lung, <i>Gallus gallus</i> variant <i>domesticus</i>: an immunocytochemical study

    2003

    View DOI
    20 cites
  22. Urea co-inclusion compounds of 13 <i>cis</i>-retinoic acid for simultaneous improvement of dissolution profile, photostability and safe handling characteristics

    2008

    View DOI
    18 cites
  23. Adduction of amiloride hydrochloride in urea through a modified technique for the dissolution enhancement

    2007

    View DOI
    18 cites
  24. Solid dispersion adsorbates for enhancement of dissolution rates of drugs.

    2007

    18 cites
  25. Application of graph theory: Models for prediction of carbonic anhydrase inhibitory activity of sulfonamides

    2006

    View DOI
    18 cites
  26. Urea co-inclusion compounds of glipizide for the improvement of dissolution profile

    2007

    View DOI
    17 cites
  27. Topochemical models for the prediction of permeability through blood–brain barrier

    2006

    View DOI
    17 cites
  28. Topological models for prediction of anti-inflammatory activity of N-arylanthranilic acids

    2004

    View DOI
    17 cites
  29. Urea inclusion compounds of enalapril maleate for the improvement of pharmaceutical characteristics

    2007

    View DOI
    16 cites
  30. Application of graph theory: prediction of glycogen synthase kinase-3 β inhibitory activity of thiadiazolidinones as potential drugs for the treatment of Alzheimer's disease

    2004

    View DOI
    16 cites
  31. Structure-Activity Study on Antiviral 5-Vinylpyrimidine Nucleoside Analogs Using Wiener's Topological Index

    1994

    View DOI
    15 cites
  32. Studies on urea co-inclusion complexes of simvastatin for improvement of pharmaceutical characteristics

    2014

    View DOI
    14 cites
  33. Topological models for prediction of heat of decomposition of urea inclusion compounds containing aliphatic endocytes

    2007

    View DOI
    14 cites
  34. Predicting biological activity: Computational approach using novel distance based molecular descriptors

    2012

    View DOI
    13 cites
  35. Topochemical model for prediction of anti-HIV activity of HEPT analogs

    2004

    View DOI
    13 cites
  36. Models for the prediction of adenosine receptors binding activity of 4-amino[1,2,4]triazolo[4,3-a]quinoxalines

    2004

    View DOI
    13 cites
  37. Simultaneous improvement in dissolution profile and content uniformity of lafutidine through co-inclusion in urea

    2015

    View DOI
    11 cites
  38. Reduction in Moisture Sensitivity/Uptake of Moisture Sensitive Drugs Through Adduction in Urea

    2008

    View DOI
    11 cites
  39. Comparison of cyclodextrins and urea as hosts for inclusion of drugs

    2017

    View DOI
    10 cites
  40. Conversion of viscous liquid malathion into free flowing solids through co-inclusion in urea for multiple benefits

    2016

    View DOI
    9 cites
  41. Prediction of Pharmacokinetic Parameters

    2012

    View DOI
    9 cites
  42. Superpendentic Index: A Novel Topological Descriptor for Predicting Biological Activity [<i>J. Chem. Inf. Comput. Sci. 39,</i> 272−277 (1999)] By

    1999

    View DOI
    9 cites
  43. Development and application of novel molecular descriptors for predicting biological activity

    2017

    View DOI
    8 cites
  44. Topological Models for Prediction of Adductability of Branched Aliphatic Compounds in Urea

    2006

    View DOI
    8 cites
  45. Immunolocalization of fibroblast growth factor-2 (FGF-2) during embryonic development of the rat submandibular gland.

    2005

    7 cites
  46. Gut microbiota modulation and health benefits of various fasting regimens

    2025

    View DOI
    6 cites
  47. Diverse models for anti-HIV activity of purine nucleoside analogs

    2015

    View DOI
    6 cites
  48. Predicting Dopamine Receptors Binding Affinity of N-[4-(4-Arylpiperazin- 1-yl) butyl]Aryl Carboxamides: Computational Approach Using Topological Descriptors

    2005

    View DOI
    6 cites
  49. STUDIES ON UREA CO-INCLUSION COMPLEXES OF EBASTINE FOR STEEP IMPROVEMENT IN DISSOLUTION PROFILE

    2017

    View DOI
    5 cites
  50. Erratum to: Improved superaugmented eccentric connectivity indices for QSAR/QSPR part I: development and evaluation

    2010

    View DOI
    5 cites
  51. Improved superaugmented eccentric connectivity indices for QSAR/QSPR part I: development and evaluation

    2009

    View DOI
    5 cites
  52. Structure-Activity Study on Antiulcer Agents Using Wiener's Topological Index and Molecular Connectivity Index

    1995

    View DOI
    5 cites
  53. Natural Chemotherapeutic Agents for Cancer

    2017

    View DOI
    4 cites
  54. Models for H3 receptor antagonist activity of sulfonylurea derivatives

    2013

    View DOI
    4 cites
  55. Models for prediction of anti- HIV-1 activity of 5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones using random forest, decision tree and moving average analysis

    2009

    View DOI
    4 cites
  56. Topological models for prediction of physico-chemical, pharmacokinetic and toxicological properties of antihistaminic drugs using decision tree and moving average analysis

    2009

    View DOI
    4 cites
  57. Topological models for prediction of adductability of substituted cyclic organic compounds in urea

    2007

    View DOI
    4 cites
  58. TOPOLOGICAL MODEL FOR THE PREDICTION OF ALPHA-1 ADRENOCEPTOR ANTAGONISTIC ACTIVITY OF ARYLPIPERAZINES

    2004

    View DOI
    4 cites
  59. Structure-activity study of antiepilepticN-aryl-isoxazolecarboxamides/N-isoxazolylbenzamide analogs using Wiener's topological index

    1997

    View DOI
    4 cites
  60. Personalized precision: Revolutionizing cancer treatment with mRNA-based vaccines in melanoma therapy

    2025

    View DOI
    3 cites
  61. Isolation &amp; Characterization of Hydrocarbon Degrading Bacteria: A Bio-remedial Approach to Clean-up Oil Spills

    2023

    View DOI
    3 cites
  62. Models for the prediction of PPARs agonistic activity of indanylacetic acids

    2012

    View DOI
    3 cites
  63. Fourth generation detour matrix-based topological indices for QSAR/QSPR - Part-1: development and evaluation

    2012

    View DOI
    3 cites
  64. Topological models for the prediction of host: guest ratio of urea inclusion compounds

    2009

    View DOI
    3 cites
  65. Predicting Acyl-Coenzyme A: Cholesterol O-Acyltransferase Inhibitory Activity: Computational Approach Using Topological Descriptors

    2003

    View DOI
    3 cites
  66. Investigations on depyrogenat10n of drugs using immobilized enzymes

    1991

    View DOI
    3 cites
  67. Dose Dependent Studies of Medicinal Extracts

    2025

    View DOI
    2 cites
  68. VACCINE DEVELOPMENT- A COMPLEX SCIENCE

    EPRA International Journal of Multidisciplinary Research (IJMR)2021journal article

    View DOI
    2 cites
  69. A Simple Technique for Palm Recognition Using Major Lines

    2017

    View DOI
    2 cites
  70. Models for anti-tumor activity of bisphosphonates using refined topochemical descriptors

    2011

    View DOI
    2 cites
  71. Improved superaugmented eccentric connectivity indices

    2011

    View DOI
    2 cites
  72. Predicting anti-allergic activity of 4-oxopyrimido [4,5-b]quinolines: Computational approach using topochemical indices

    2007

    View DOI
    2 cites
  73. Topochemical models for anti-HIV activity of 1-alkoxy-5-alkyl-6-(arylthio)uracils

    2007

    View DOI
    2 cites
  74. Topochemical models for predicting the activity of α,γ-diketo acids as inhibitors of the hepatitis c virus NS5B RNA-dependent RNA polymerase

    2006

    View DOI
    2 cites
  75. Topochemical Models for Prediction of Anti-HIV Activity of 4-Benzyl Pyridinone Derivatives

    2005

    View DOI
    2 cites
  76. Highly distorted urea based channel lattice complexes as an alternative to solid dispersions for improving content uniformity and dissolution rate

    2002

    View DOI
    2 cites
  77. Biomaterials in Clinical Trials and Clinical Applications

    Biomaterials and Neurodegenerative Disorders1970book chapter

    View DOI
    2 cites
  78. Emerging Global Technologies in Veterinary Sciences

    2025

    View DOI
    1 cites
  79. Ethical Considerations in Stem Cell Therapeutics

    2025

    View DOI
    1 cites
  80. Modes of Action of Biocontrol Agents from Rhizosphere to Phyllosphere Signaling

    2025

    View DOI
    1 cites
  81. Impact of Diet, Microbiota, and Postbiotics in Colorectal Cancer (CRC) Management

    2025

    View DOI
    1 cites
  82. Classification Models Using Decision Tree, Random Forest, and Moving Average Analysis

    2020

    View DOI
    1 cites
  83. Randic Index and Its Variants: Applications

    2020

    View DOI
    1 cites
  84. Studies on cysteine proteases and their inhibitors for anticancer drug design

    2020

    View DOI
    1 cites
  85. Improvement in Rheological, Safe Handling and Formulation Characteristics of Viscous Cypermethrin Through Co-inclusion in Urea

    2019

    View DOI
    1 cites
  86. Path Pendeccentric Connectivity Indices: Detour Matrix Based Molecular Descriptors for QSAR/QSPR Studies, Part 2

    2017

    View DOI
    1 cites
  87. Detour matrix-based adjacent path eccentric distance sum indices for QSAR/QSPR. Part I: development and evaluation

    2014

    View DOI
    1 cites
  88. Diverse models for the prediction of CDK4 inhibitory activity of substituted 4-aminomethylene isoquinoline-1, 3-diones

    2013

    View DOI
    1 cites
  89. Studies on Flash Evaporation for Preparation of Porous Solid Dispersions Using Piroxicam as a Model Drug

    2011

    View DOI
    1 cites
  90. Models for anti-inflammatory activity of 8-substituted-4-anilino-6-aminoquinoline-3-carbonitriles

    2011

    View DOI
    1 cites
  91. Prediction of the agonist allosteric enhancer activity of thiophenes with respect to human A1 adenosine receptors using topological indices

    2007

    View DOI
    1 cites
  92. TOPOLOGICAL MODELS FOR THE PREDICTION OF NEUTRAL ENDOPEPTIDASE AND ANGIOTENSIN-CONVERTING ENZYME INHIBITORY ACTIVITY OF MERCAPTOACYLDIPEPTIDES

    2006

    View DOI
    1 cites
  93. ChemInform Abstract: Eccentric Connectivity Index: A Novel Highly Discriminating Topological Descriptor for Structure‐Property and Structure‐Activity Studies

    1997

    View DOI
    1 cites
  94. Hydroponics/Aquaponics and Its Co-benefits

    Wastewater Treatment Through Nature-Based Solutions1970book chapter

    View DOI
    1 cites
  95. Scaling up of secondary metabolite production

    Secondary Metabolites and Biotherapeutics1970book chapter

    View DOI
    1 cites
  96. Tools and Technologies for Studying Cancer Metabolism

    2026

    View DOI
    0 cites
  97. Gold and Silver Nanoparticles in Biomedical Applications: Cytotoxicity, Mechanism of Action, and Future Challenges

    2025

    View DOI
    0 cites
  98. Different Vegetables and Their Nutraceutical Significances

    2025

    View DOI
    0 cites
  99. Physicochemical and Heavy Metal Analysis of Military Drinking Water in Makurdi

    Trends in Environmental Sciences2025journal article

    View DOI
    0 cites
  100. CRISPR‐Cas9 and Beyond

    2025

    View DOI
    0 cites
  101. Postbiotics

    2025

    View DOI
    0 cites
  102. Effect of different concentration of mineral fertilizers on growth and yield of Curcuma longa L. in Surkhandarya region, Uzbekis tan

    2025

    View DOI
    0 cites
  103. 0 cites
  104. Comparative morphological study of the gastrointestinal tract of Eutropius niloticus and Oreochromis niloticus from lower river Benue, Nigeria

    2025

    View DOI
    0 cites
  105. Biomaterials for Regenerative Medicine: Historical Perspectives and Current Trends

    2025

    View DOI
    0 cites
  106. Revolutionizing Communication in Mechanical Engineering Applications through 5G Connectivity

    2024

    View DOI
    0 cites
  107. Contributors

    2024

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    0 cites
  108. FOREST THERAPY: EXPLORING THE MEDICINAL SECRETS OF NATURE'S GREEN PHARMACY

    2023

    View DOI
    0 cites
  109. Review and Prospect of Process Research on Large Forgings

    2022

    View DOI
    0 cites
  110. Recent Advances in Various Types of Forging - A Research Review

    2021

    View DOI
    0 cites
  111. Topology-Based Molecular Descriptors: The Current Status

    2020

    View DOI
    0 cites
  112. Superaugmented Eccentric Connectivity Indices and Their Significance in Drug Discovery Process

    2020

    View DOI
    0 cites
  113. Pendentancy-Based Molecular Descriptors for QSAR/QSPR Studies

    2020

    View DOI
    0 cites
  114. (Q)SPR Models for Prediction of Hydrophobicity of Isatins

    2017

    View DOI
    0 cites
  115. Path Pendeccentric Connectivity Indices: Detour Matrix Based Molecular Descriptors for QSAR/QSPR Studies, Part 1

    2017

    View DOI
    0 cites
  116. In Silico Classification Models for Anticancer Drugs

    2015

    View DOI
    0 cites
  117. Role of Moving Average Analysis for Development of Multi-Target (Q)SAR Models

    2015

    View DOI
    0 cites
  118. Diverse Models for the Prediction of Dual mTOR and PI3K&amp;#945; Inhibitory Activities of Substituted 4-morpholinopyrrolopyrimidines

    2014

    View DOI
    0 cites
  119. Relative Eccentric Distance Sum/Product Indices for QSAR/QSPR: Development, Evaluation, and Application

    2014

    View DOI
    0 cites
  120. Detour matrix-based adjacent path eccentric distance sum indices for (Q)SAR/QSPR. Part II: application in development of models for COX-2 inhibitory activity of indomethacin derivatives

    2014

    View DOI
    0 cites
  121. Fourth generation detour matrix-based topological descriptors for QSAR/QSPR - Part-2: application in development of models for prediction of biological activity

    2014

    View DOI
    0 cites
  122. Models for the prediction of melanocortin-4 receptor agonist activity of 4-substituted piperidin-4-ol

    2013

    View DOI
    0 cites
  123. Models for Cannabinoid-1 Receptor Antagonistic Activity of Substituted 2-(3-Pyrazolyl)-1,3,4-Oxadiazoles

    2010

    View DOI
    0 cites
  124. Models for Prediction of <sup>V600E</sup>BRAF and Melanoma Cells Growth Inhibitory Activities of Pyridoimidazolones

    2010

    View DOI
    0 cites
  125. Urea as an adductor for the branched drug molecules

    2010

    0 cites
  126. Topochemical models for the prediction of poly(ADP-ribose) polymerase inhibitory activity of indole-1-ones

    2007

    View DOI
    0 cites
  127. Топохимические индексы для предсказания активности тиофенов как аллостерических эффекторов A1-аденозин рецепторов человека

    2007

    View DOI
    0 cites
  128. Топохимические модели для предсказания активности α,γ-дикетокислот в отношении РНК-зависимой РНК-полимеразы вируса гепатита C

    2006

    0 cites
  129. Predicting carbonic anhydrase inhibitory activity of sulfonamides: computational approach using topological descriptors

    2005

    View DOI
    0 cites
  130. ChemInform Abstract: Superpendentic Index: A Novel Topological Descriptor for Predicting Biological Activity.

    1999

    View DOI
    0 cites
  131. ChemInform Abstract: TETRAHYDRO(1)BENZOTHIENO(2,3‐D)PYRIMIDINES

    1979

    View DOI
    0 cites
  132. ChemInform Abstract: BENZOTHIENO(2,3‐D)THIAZOLO(3,2‐A)PYRIMIDINES

    1979

    View DOI
    0 cites
  133. Biotechnological Framework for the Treatment of Environmental Pollution and Challenges Thereof

    Sustainable Biotechnological Remedial Frameworks for the Rejuvenation of Heavily Polluted Environments1970book chapter

    View DOI
    0 cites
  134. Advanced Bioreactor Systems and Design Principles for Scalable Bio-Manufacturing

    Industrial Applications for Bioprocessing and Biomanufacturing1970book chapter

    View DOI
    0 cites
  135. AI technologies for enhancing recycling processes

    AI Technologies for Enhancing Recycling Processes1970book

    View DOI
    0 cites
  136. Cell free systems for biodesign

    Progress in Molecular Biology and Translational Science1970book

    View DOI
    0 cites
  137. Isolation, Characterization, and Detailed History of Exosomes Derived from Stem Cells and their Epigenetic Biology

    Applications of Stem Cells and derived Exosomes in Neurodegenerative Disorders1970book chapter

    View DOI
    0 cites