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Citations
330

via OpenAlex

Publications
15

About

Brij Sharma is a researcher at Government Medical College, with a focus on quantitative structure-activity relationship (QSAR) studies and chemometric approaches. Over the course of 14 years, from 2008 to 2022, Sharma has published 15 papers on topics such as ATP-sensitive potassium channel activation, caspase-3 inhibition, carbonic anhydrase inhibition, and human histamine H4 receptor ligands.

Research areas

  • Medicine
  • Quantitative structure–activity relationship
  • Chemistry
  • Internal medicine
  • Stereochemistry

Publications (15)

Sorted by most cited.

  1. QSAR study about ATP-sensitive potassium channel activation of cromakalim analogues using CP-MLR approach

    2008

    View DOI
    35 cites
  2. Combinatorial protocol in multiple linear regression/partial least-squares directed rationale for the caspase-3 inhibition activity of isoquinoline-1,3,4-trione derivatives

    2010

    View DOI
    25 cites
  3. Chemometric descriptors in modeling the carbonic anhydrase inhibition activity of sulfonamide and sulfamate derivatives

    2009

    View DOI
    21 cites
  4. Juglone derivatives as antitubercular agents: A rationale for the activity profile

    2008

    View DOI
    21 cites
  5. QSAR of 2-(4-methylsulphonylphenyl)pyrimidine derivatives as cyclooxygenase-2 inhibitors: simple structural fragments as potential modulators of activity

    2011

    View DOI
    10 cites
  6. A QSAR study on 2-(4-methylpiperazin-1-yl)quinoxalines as human histamine H<sub>4</sub>receptor ligands

    2010

    View DOI
    8 cites
  7. CP-MLR directed QSAR study of carbonic anhydrase inhibitors: sulfonamide and sulfamate inhibitors

    2009

    View DOI
    8 cites
  8. Quantitative structure-activity relationship study on the MMP-13 inhibitory activity of fused pyrimidine derivatives possessing a 1,2,4-Triazol-3-yl group as a ZBG

    2021

    View DOI
    5 cites
  9. Modeling of the growth hormone secretagogue receptor antagonistic activity using chemometric tools

    2009

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    4 cites
  10. A Combined QSAR and Molecular Docking Approach for Identifying Pyrimidine Derivatives as Penicillin Binding Protein Inhibitors

    2022

    View DOI
    3 cites
  11. QSAR Study on 5-Lipoxygenase Activating Protein (FLAP) Inhibitors: The Derivatives of 2,2-Bisaryl-Bicycloheptane

    2010

    View DOI
    3 cites
  12. CP-MLR/PLS directed quantitative structure-activity relationship study on the CDK8 inhibitory activity: The derivatives of naphthyridine and isoquinoline

    2022

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    2 cites
  13. CP-MLR/PLS directed quantitative structure-activity relationship study on the histamine H3 receptor binding affinity: The cyclohexylamine based series

    2023

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    1 cites
  14. Quantitative structure-activity relationship study on the CDK2 inhibitory activity of 6-substituted 2-arylaminopurines

    2022

    View DOI
    1 cites
  15. CP-MLR derived QSAR study on the PPARγ agonists: The benzylpyrazole acylsulfonamide derivatives

    2020

    View DOI
    0 cites