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Citations
332

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Publications
70

About

Brij Sharma is a researcher at Government Medical College, with a focus on quantitative structure-activity relationship (QSAR) studies and chemometric approaches. Over the course of 14 years, from 2008 to 2022, Sharma has published 15 papers on topics such as ATP-sensitive potassium channel activation, caspase-3 inhibition, carbonic anhydrase inhibition, and human histamine H4 receptor ligands.

Research areas

  • Medicine
  • Quantitative structure–activity relationship
  • Chemistry
  • Internal medicine
  • Stereochemistry

Publications (70)

Sorted by most cited.

  1. QSAR study about ATP-sensitive potassium channel activation of cromakalim analogues using CP-MLR approach

    2008

    View DOI
    35 cites
  2. Topological descriptors in modeling the agonistic activity of human A3 adenosine receptor ligands: The derivatives of 2-chloro-N6-substituted-4′-thioadenosine-5′-uronamide

    2008

    View DOI
    32 cites
  3. Depletion of Organic Carbon, Phosphorus, and Potassium Stock Under a Pearl Millet Based Cropping System in the Arid Region of India

    2007

    View DOI
    27 cites
  4. Combinatorial protocol in multiple linear regression/partial least-squares directed rationale for the caspase-3 inhibition activity of isoquinoline-1,3,4-trione derivatives

    2010

    View DOI
    25 cites
  5. Chemometric descriptors in modeling the carbonic anhydrase inhibition activity of sulfonamide and sulfamate derivatives

    2009

    View DOI
    21 cites
  6. Juglone derivatives as antitubercular agents: A rationale for the activity profile

    2008

    View DOI
    21 cites
  7. A Prospective Randomised Comparative Four-arm Intervention Study of Efficacy and Safety of Saroglitazar and Vitamin E in Patients With Non-alcoholic Fatty Liver Disease (NAFLD)/Non-alcoholic Steatohepatitis (NASH)-SVIN TRIAL

    2024

    View DOI
    17 cites
  8. A rationale for the activity profile of arylpiperazinylthioalkyls as 5-HT1A-serotonin and α1-adrenergic receptor ligands

    2010

    View DOI
    15 cites
  9. Four percent formalin application for the management of radiation proctitis in carcinoma cervix patients: An effective, safe, and economical practice

    2018

    View DOI
    13 cites
  10. QSAR of 2-(4-methylsulphonylphenyl)pyrimidine derivatives as cyclooxygenase-2 inhibitors: simple structural fragments as potential modulators of activity

    2011

    View DOI
    10 cites
  11. CP-MLR/PLS directed QSAR study on apical sodium-codependent bile acid transporter inhibition activity of benzothiepines

    2010

    View DOI
    10 cites
  12. Acute kidney injury in acute liver failure: A narrative review

    2024

    View DOI
    9 cites
  13. Topological and Physicochemical Characteristics of 1,2,3,4-Tetrahydroacridin- 9(10H)-Ones and Their Antimalarial Profiles: A Composite Insight to the Structure-Activity Relation<sup>§</sup>

    2013

    View DOI
    8 cites
  14. A QSAR study on 2-(4-methylpiperazin-1-yl)quinoxalines as human histamine H<sub>4</sub>receptor ligands

    2010

    View DOI
    8 cites
  15. CP-MLR directed QSAR study of carbonic anhydrase inhibitors: sulfonamide and sulfamate inhibitors

    2009

    View DOI
    8 cites
  16. Vitamin D Status in Cold Trans-Himalayan Deserts at Altitude of 4000 meter and above in India

    2018

    View DOI
    7 cites
  17. A Robust EfficientNet Architecture for Brain Tumor Classification and Identification Using MRI Image

    2023

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    6 cites
  18. Etiology of ascites in adults living in the Hills of Himachal Pradesh, India: A hospital-based study

    2015

    View DOI
    6 cites
  19. Chemometric Descriptor Based QSAR Rationales for the MMP-13 Inhibition Activity of Non-Zinc-Chelating Compounds

    2013

    View DOI
    6 cites
  20. A rationale for the activity profile of benzenesulfonamide derivatives as cyclooxygenase (COX) inhibitors

    2010

    View DOI
    6 cites
  21. Modeling of the growth hormone secretagogue receptor antagonistic activity using chemometric tools

    2009

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    4 cites
  22. A Combined QSAR and Molecular Docking Approach for Identifying Pyrimidine Derivatives as Penicillin Binding Protein Inhibitors

    2022

    View DOI
    3 cites
  23. Patients with metabolic-dysfunction associated fatty liver disease (MAFLD) without associated etiologies and non-MAFLD non-alcoholic fatty liver disease (NAFLD) have similar liver disease severity - Data from Indian Consortium on NAFLD (ICON-D).

    2022

    View DOI
    3 cites
  24. Analysis of Activation Functions for Convolutional Neural Network based MNIST Handwritten Character Recognition

    2019

    3 cites
  25. QSAR rationales for the 1,2-diarylcyclopentenes as prostaglandin EP1 receptor antagonists: Potentially useful in the treatment of inflammatory pain

    2010

    View DOI
    3 cites
  26. QSAR Study on 5-Lipoxygenase Activating Protein (FLAP) Inhibitors: The Derivatives of 2,2-Bisaryl-Bicycloheptane

    2010

    View DOI
    3 cites
  27. 2D-QSAR and molecular docking study on nitrofuran analogues as antitubercular agents

    2024

    View DOI
    2 cites
  28. CP-MLR Directed QSAR Rationales for the 1-aryl Sulfonyl Tryptamines as 5-HT6 Receptor Ligands

    2015

    View DOI
    2 cites
  29. A QSAR Study on ATP-Sensitive Potassium Channel Openers : The Derivatives of 3-Alkylamino-4h-1, 2, 4-Benzothiadiazine 1, 1-Dioxide

    2009

    2 cites
  30. Correlation of endoscopic findings, histopathological features and Helicobacter pylori infection in adult dyspeptic patients from the cold desert tribal region of Spiti Valley, Himachal Pradesh

    2025

    View DOI
    1 cites
  31. CP-MLR/PLS-guided Quantitative Structure-activity Relationship Study on the Derivatives of Benzimidazolone as H<sub>3</sub>-Antihistaminic Agents

    2025

    View DOI
    1 cites
  32. FRI-231 Compared to complete abstainers, non-significant alcohol use may be associated with more severe liver disease in patients with metabolic dysfunction-associated steatotic liver disease (MASLD)-The multicentre study of the indian consortium on MASLD

    2024

    View DOI
    1 cites
  33. Exploration of Potential Cyclin-dependent Kinases and their Inhibitors toCombat Abnormal Signalling and Cancer

    2024

    View DOI
    1 cites
  34. A rare cause of obscure overt GI bleeding diagnosed by digital pancreatoscopy (with videos)

    2023

    View DOI
    1 cites
  35. Gastric Outlet Obstruction: Don’t Miss Duodenal Tuberculosis

    2022

    View DOI
    1 cites
  36. CP-MLR DIRECTED QSAR RATIONALES FOR THE ACTIVITY PROFILE OF (PHENYLPIPERAZINYL-ALKYL) OXINDOLES AS 5-HT7 RECEPTOR LIGANDS

    2015

    View DOI
    1 cites
  37. QSAR Study Of Dihydropyrimidinone C-5 Amides As The Selective ?1a-Receptor Antagonists

    2003

    1 cites
  38. Prevalence and Severity of Metabolic Dysfunction-Associated Steatotic Liver Disease Among Patients with Gallstone Disease: A Prospective Hospital-Based Study

    2025

    View DOI
    0 cites
  39. Food Residue in Biliary Tract: A Rare Cause of Cholangitis

    2025

    View DOI
    0 cites
  40. A Novel CNN-Based Approach for Cervix Cancer Type Classification

    2025

    View DOI
    0 cites
  41. Impact of a month-long Religious Diurnal Fasting (Ramadan) on Hepatic Steatosis, stiffness, and Anthropo-metabolic Indices

    2025

    View DOI
    0 cites
  42. Impact of Low to Moderate Alcohol Consumption on Hepatic Fibrosis Severity in Patients with MASLD: Insights from 7189 patients from ICOM-D Consortium

    2025

    View DOI
    0 cites
  43. An Often Overlooked Cause of Iron Deficiency in Adults

    2024

    View DOI
    0 cites
  44. Acute Gastrointestinal Bleed in Adults – Part B

    2024

    View DOI
    0 cites
  45. Acute Gastrointestinal Bleed in Adults – Part A

    2024

    View DOI
    0 cites
  46. Jaundice

    2024

    View DOI
    0 cites
  47. Liver Failure

    2024

    View DOI
    0 cites
  48. Change in nomenclature and definition from NAFLD to MASLD maintains the disease severity determining association between type 2 DM and MASLD - The results of multi-centre Indian Consortium on MASLD (ICOM-D)

    2024

    View DOI
    0 cites
  49. A Case of Spontaneous Rectal Perforation in a Constipated Elderly Patient

    2024

    View DOI
    0 cites
  50. Modelling of the Cyclic Guanidines as 5 ‐ HT5A Receptor Ligands Using Chemometric Tools

    2024

    View DOI
    0 cites
  51. CP-MLR/PLS directed quantitative structure-activity relationship study on the histamine H3 receptor binding affinity: The cyclohexylamine based series

    2023

    View DOI
    0 cites
  52. CP-MLR/PLS directed quantitative structure-activity relationship study on the CDK8 inhibitory activity: The derivatives of naphthyridine and isoquinoline

    2022

    View DOI
    0 cites
  53. Preprocedural Nebulisation with 4% Lignocaine and Ketofol Sedation during Endoscopic Retrograde Cholangiopancreatography Procedure for Abolition of Gag Reflex: A Randomised Double-blinded Study

    2022

    View DOI
    0 cites
  54. Quantitative Structure-Activity Relationship Study on the CDK4/6 Inhibitory Activity: The 4-Thiazol-N-(pyridin-2-yl)pyrimidin-2-amines

    2022

    View DOI
    0 cites
  55. Intrathoracic Chronic Gastric Volvulus Secondary to Paraesophageal Hernia in a Young Adult: A Case Report

    2022

    View DOI
    0 cites
  56. Quantitative structure-activity relationship study on the CDK2 inhibitory activity of 6-substituted 2-arylaminopurines

    2022

    View DOI
    0 cites
  57. Primary Mucoepidermoid Carcinoma of Esophagus: A Rare Case Report

    2022

    View DOI
    0 cites
  58. CRP as a biomarker of inflammation in Non-alcoholic fatty liver disease

    2022

    View DOI
    0 cites
  59. Quantitative structure-activity relationship study on the MMP-13 inhibitory activity of fused pyrimidine derivatives possessing a 1,2,4-Triazol-3-yl group as a ZBG

    2021

    View DOI
    0 cites
  60. Primary Malignant Melanoma of the Stomach

    2021

    View DOI
    0 cites
  61. CP-MLR Directed QSAR Rationales for the 1-aryl Sulfonyl Tryptamines as 5-HT6 Receptor Ligands: An Advanced Study

    2021

    View DOI
    0 cites
  62. CP-MLR derived QSAR study on the PPARγ agonists: The benzylpyrazole acylsulfonamide derivatives

    2020

    View DOI
    0 cites
  63. QSAR study on the hGPR119 Agonistic Activity of Triazolopyridines

    2020

    View DOI
    0 cites
  64. QSAR study on the Dipeptide-Derived Inhibitor of Dipeptidyl Peptidase IV: The (2S)-Cyanopyrrolidine analogues

    2020

    View DOI
    0 cites
  65. Author’s reply

    2014

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    0 cites
  66. An Anthropological Account of Bonhomie and Opprobrium between Communities and Animals in Rajasthan

    2013

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    0 cites
  67. Advances in Structure–Activity Relationship Studies on Potassium Channel Modulators

    2011

    View DOI
    0 cites
  68. A QSAR STUDY ON 5-HT7 RECEPTOR ANTAGONISTS: DERIVATIVES OF (PHENYLPIPERAZINYL-ALKYL) OXINDOLE

    2009

    0 cites
  69. DECLINING AVIFAUNAL DIVERSITY OF SAMBHARLAKE IS AN IMPORTANT BIO-INDICATOR OF THE ILL-HEALTH OF THE LAKE

    2008

    0 cites
  70. QSAR analysis of heteroaryl derivatives of 1,2-diarylimidazole with cyclooxygenase-2 inhibitory activity

    2002

    0 cites