- h-index
- 10
- Citations
- 332
- Publications
- 70
via OpenAlex
via OpenAlex
About
Brij Sharma is a researcher at Government Medical College, with a focus on quantitative structure-activity relationship (QSAR) studies and chemometric approaches. Over the course of 14 years, from 2008 to 2022, Sharma has published 15 papers on topics such as ATP-sensitive potassium channel activation, caspase-3 inhibition, carbonic anhydrase inhibition, and human histamine H4 receptor ligands.
Research areas
- Medicine
- Quantitative structure–activity relationship
- Chemistry
- Internal medicine
- Stereochemistry
Publications (70)
Sorted by most cited.
- 35 cites
QSAR study about ATP-sensitive potassium channel activation of cromakalim analogues using CP-MLR approach
2008
View DOI - 32 cites
Topological descriptors in modeling the agonistic activity of human A3 adenosine receptor ligands: The derivatives of 2-chloro-N6-substituted-4′-thioadenosine-5′-uronamide
2008
View DOI - 27 cites
Depletion of Organic Carbon, Phosphorus, and Potassium Stock Under a Pearl Millet Based Cropping System in the Arid Region of India
2007
View DOI - 25 cites
Combinatorial protocol in multiple linear regression/partial least-squares directed rationale for the caspase-3 inhibition activity of isoquinoline-1,3,4-trione derivatives
2010
View DOI - 21 cites
Chemometric descriptors in modeling the carbonic anhydrase inhibition activity of sulfonamide and sulfamate derivatives
2009
View DOI - 21 cites
- 17 cites
A Prospective Randomised Comparative Four-arm Intervention Study of Efficacy and Safety of Saroglitazar and Vitamin E in Patients With Non-alcoholic Fatty Liver Disease (NAFLD)/Non-alcoholic Steatohepatitis (NASH)-SVIN TRIAL
2024
View DOI - 15 cites
A rationale for the activity profile of arylpiperazinylthioalkyls as 5-HT1A-serotonin and α1-adrenergic receptor ligands
2010
View DOI - 13 cites
Four percent formalin application for the management of radiation proctitis in carcinoma cervix patients: An effective, safe, and economical practice
2018
View DOI - 10 cites
QSAR of 2-(4-methylsulphonylphenyl)pyrimidine derivatives as cyclooxygenase-2 inhibitors: simple structural fragments as potential modulators of activity
2011
View DOI - 10 cites
CP-MLR/PLS directed QSAR study on apical sodium-codependent bile acid transporter inhibition activity of benzothiepines
2010
View DOI - 9 cites
- 8 cites
Topological and Physicochemical Characteristics of 1,2,3,4-Tetrahydroacridin- 9(10H)-Ones and Their Antimalarial Profiles: A Composite Insight to the Structure-Activity Relation<sup>§</sup>
2013
View DOI - 8 cites
A QSAR study on 2-(4-methylpiperazin-1-yl)quinoxalines as human histamine H<sub>4</sub>receptor ligands
2010
View DOI - 8 cites
CP-MLR directed QSAR study of carbonic anhydrase inhibitors: sulfonamide and sulfamate inhibitors
2009
View DOI - 7 cites
Vitamin D Status in Cold Trans-Himalayan Deserts at Altitude of 4000 meter and above in India
2018
View DOI - 6 cites
A Robust EfficientNet Architecture for Brain Tumor Classification and Identification Using MRI Image
2023
View DOI - 6 cites
Etiology of ascites in adults living in the Hills of Himachal Pradesh, India: A hospital-based study
2015
View DOI - 6 cites
Chemometric Descriptor Based QSAR Rationales for the MMP-13 Inhibition Activity of Non-Zinc-Chelating Compounds
2013
View DOI - 6 cites
A rationale for the activity profile of benzenesulfonamide derivatives as cyclooxygenase (COX) inhibitors
2010
View DOI - 4 cites
Modeling of the growth hormone secretagogue receptor antagonistic activity using chemometric tools
2009
View DOI - 3 cites
A Combined QSAR and Molecular Docking Approach for Identifying Pyrimidine Derivatives as Penicillin Binding Protein Inhibitors
2022
View DOI - 3 cites
Patients with metabolic-dysfunction associated fatty liver disease (MAFLD) without associated etiologies and non-MAFLD non-alcoholic fatty liver disease (NAFLD) have similar liver disease severity - Data from Indian Consortium on NAFLD (ICON-D).
2022
View DOI - 3 cites
Analysis of Activation Functions for Convolutional Neural Network based MNIST Handwritten Character Recognition
2019
- 3 cites
QSAR rationales for the 1,2-diarylcyclopentenes as prostaglandin EP1 receptor antagonists: Potentially useful in the treatment of inflammatory pain
2010
View DOI - 3 cites
QSAR Study on 5-Lipoxygenase Activating Protein (FLAP) Inhibitors: The Derivatives of 2,2-Bisaryl-Bicycloheptane
2010
View DOI - 2 cites
- 2 cites
CP-MLR Directed QSAR Rationales for the 1-aryl Sulfonyl Tryptamines as 5-HT6 Receptor Ligands
2015
View DOI - 2 cites
A QSAR Study on ATP-Sensitive Potassium Channel Openers : The Derivatives of 3-Alkylamino-4h-1, 2, 4-Benzothiadiazine 1, 1-Dioxide
2009
- 1 cites
Correlation of endoscopic findings, histopathological features and Helicobacter pylori infection in adult dyspeptic patients from the cold desert tribal region of Spiti Valley, Himachal Pradesh
2025
View DOI - 1 cites
CP-MLR/PLS-guided Quantitative Structure-activity Relationship Study on the Derivatives of Benzimidazolone as H<sub>3</sub>-Antihistaminic Agents
2025
View DOI - 1 cites
FRI-231 Compared to complete abstainers, non-significant alcohol use may be associated with more severe liver disease in patients with metabolic dysfunction-associated steatotic liver disease (MASLD)-The multicentre study of the indian consortium on MASLD
2024
View DOI - 1 cites
Exploration of Potential Cyclin-dependent Kinases and their Inhibitors toCombat Abnormal Signalling and Cancer
2024
View DOI - 1 cites
A rare cause of obscure overt GI bleeding diagnosed by digital pancreatoscopy (with videos)
2023
View DOI - 1 cites
- 1 cites
CP-MLR DIRECTED QSAR RATIONALES FOR THE ACTIVITY PROFILE OF (PHENYLPIPERAZINYL-ALKYL) OXINDOLES AS 5-HT7 RECEPTOR LIGANDS
2015
View DOI - 1 cites
QSAR Study Of Dihydropyrimidinone C-5 Amides As The Selective ?1a-Receptor Antagonists
2003
- 0 cites
Prevalence and Severity of Metabolic Dysfunction-Associated Steatotic Liver Disease Among Patients with Gallstone Disease: A Prospective Hospital-Based Study
2025
View DOI - 0 cites
- 0 cites
- 0 cites
Impact of a month-long Religious Diurnal Fasting (Ramadan) on Hepatic Steatosis, stiffness, and Anthropo-metabolic Indices
2025
View DOI - 0 cites
Impact of Low to Moderate Alcohol Consumption on Hepatic Fibrosis Severity in Patients with MASLD: Insights from 7189 patients from ICOM-D Consortium
2025
View DOI - 0 cites
- 0 cites
- 0 cites
- 0 cites
- 0 cites
- 0 cites
Change in nomenclature and definition from NAFLD to MASLD maintains the disease severity determining association between type 2 DM and MASLD - The results of multi-centre Indian Consortium on MASLD (ICOM-D)
2024
View DOI - 0 cites
- 0 cites
- 0 cites
CP-MLR/PLS directed quantitative structure-activity relationship study on the histamine H3 receptor binding affinity: The cyclohexylamine based series
2023
View DOI - 0 cites
CP-MLR/PLS directed quantitative structure-activity relationship study on the CDK8 inhibitory activity: The derivatives of naphthyridine and isoquinoline
2022
View DOI - 0 cites
Preprocedural Nebulisation with 4% Lignocaine and Ketofol Sedation during Endoscopic Retrograde Cholangiopancreatography Procedure for Abolition of Gag Reflex: A Randomised Double-blinded Study
2022
View DOI - 0 cites
Quantitative Structure-Activity Relationship Study on the CDK4/6 Inhibitory Activity: The 4-Thiazol-N-(pyridin-2-yl)pyrimidin-2-amines
2022
View DOI - 0 cites
Intrathoracic Chronic Gastric Volvulus Secondary to Paraesophageal Hernia in a Young Adult: A Case Report
2022
View DOI - 0 cites
Quantitative structure-activity relationship study on the CDK2 inhibitory activity of 6-substituted 2-arylaminopurines
2022
View DOI - 0 cites
- 0 cites
- 0 cites
Quantitative structure-activity relationship study on the MMP-13 inhibitory activity of fused pyrimidine derivatives possessing a 1,2,4-Triazol-3-yl group as a ZBG
2021
View DOI - 0 cites
- 0 cites
CP-MLR Directed QSAR Rationales for the 1-aryl Sulfonyl Tryptamines as 5-HT6 Receptor Ligands: An Advanced Study
2021
View DOI - 0 cites
CP-MLR derived QSAR study on the PPARγ agonists: The benzylpyrazole acylsulfonamide derivatives
2020
View DOI - 0 cites
- 0 cites
QSAR study on the Dipeptide-Derived Inhibitor of Dipeptidyl Peptidase IV: The (2S)-Cyanopyrrolidine analogues
2020
View DOI - 0 cites
- 0 cites
An Anthropological Account of Bonhomie and Opprobrium between Communities and Animals in Rajasthan
2013
View DOI - 0 cites
- 0 cites
A QSAR STUDY ON 5-HT7 RECEPTOR ANTAGONISTS: DERIVATIVES OF (PHENYLPIPERAZINYL-ALKYL) OXINDOLE
2009
- 0 cites
DECLINING AVIFAUNAL DIVERSITY OF SAMBHARLAKE IS AN IMPORTANT BIO-INDICATOR OF THE ILL-HEALTH OF THE LAKE
2008
- 0 cites
QSAR analysis of heteroaryl derivatives of 1,2-diarylimidazole with cyclooxygenase-2 inhibitory activity
2002