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Chandrabose Karthikeyan

University of Arkansas for Medical SciencesIN
ORCID0000-0002-9074-9554
h-index
28

via OpenAlex

Citations
2,404

via OpenAlex

Publications
171

About

Chandrabose Karthikeyan is a researcher at the University of Arkansas for Medical Sciences. With over 104 publications spanning from 1970 to 2026, his work primarily focuses on quantitative structure-activity relationships (QSAR) and their applications in medicinal chemistry, particularly in the areas of anti-cancer agents, anti-inflammatory compounds, and targeted drug delivery.

Research areas

  • Chemistry
  • Medicine
  • Biology
  • Biochemistry
  • Organic chemistry

Publications (171)

Sorted by most cited.

  1. Advances in Chalcones with Anticancer Activities

    2014

    View DOI
    278 cites

  2. A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinoma

    Oncotarget1970journal article

    View DOI
    100 cites

  3. Human CDC2-like kinase 1 (CLK1): A novel target for Alzheimer's disease

    Current Drug Targets1970journal article

    View DOI
    96 cites

  4. Performance of SBR for the treatment of textile dye wastewater: Optimization and kinetic studies

    2014

    View DOI
    86 cites

  5. Novel quinolone chalcones targeting colchicine-binding pocket kill multidrug-resistant cancer cells by inhibiting tubulin activity and MRP1 function

    Scientific Reports1970journal article

    View DOI
    76 cites

  6. Recent advances in protein tyrosine phosphatase 1b targeted drug discovery for Type II diabetes and obesity

    Current Drug Targets1970journal article

    View DOI
    71 cites

  7. The Rise and Fall of Chloroquine/Hydroxychloroquine as Compassionate Therapy of COVID-19

    Frontiers in Pharmacology1970journal article

    View DOI
    66 cites

  8. Design, synthesis and biological evaluation of some isatin-linked chalcones as novel anti-breast cancer agents: A molecular hybridization approach

    Biomedicine and Preventive Nutrition1970journal article

    View DOI
    65 cites

  9. Synthesis, characterization and anti cancer activity of some fluorinated 3,6-diaryl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles

    Arabian Journal of Chemistry1970journal article

    View DOI
    54 cites

  10. 6H-indolo[2,3-b]quinoxalines: DNA and protein interacting scaffold for pharmacological activities

    Mini-Reviews in Medicinal Chemistry1970journal article

    View DOI
    54 cites

  11. Natural polysaccharides: Structural features and properties

    Polysaccharide Carriers for Drug Delivery1970book chapter

    View DOI
    52 cites

  12. Thienopyrimidine derivatives exert their anticancer efficacy via apoptosis induction, oxidative stress and mitotic catastrophe

    European Journal of Medicinal Chemistry1970journal article

    View DOI
    50 cites

  13. Performance evaluation of SBR for the treatment of dyeing wastewater by simultaneous biological and adsorption processes

    2014

    View DOI
    46 cites

  14. Synthesis of Some Coumarinyl Chalcones and their Antiproliferative Activity Against Breast Cancer Cell Lines

    2011

    View DOI
    45 cites

  15. IND-2, a pyrimido[1¿,2¿:1,5]pyrazolo[3,4-b]quinoline derivative, circumvents multi-drug resistance and causes apoptosis in colon cancer cells

    Bioorganic and Medicinal Chemistry1970journal article

    View DOI
    45 cites

  16. Predicting the Stages of Diabetic Retinopathy using Deep Learning

    2021

    View DOI
    40 cites

  17. Design, synthesis and biological evaluation of some novel 3-cinnamoyl-4-hydroxy-2H-chromen-2-ones as antimalarial agents

    Medicinal Chemistry Research1970journal article

    View DOI
    39 cites

  18. Microwave-Assisted Functionalization of Multi-Walled Carbon Nanotubes for Biosensor and Drug Delivery Applications

    Pharmaceutics1970journal article

    View DOI
    38 cites

  19. Recent advances in the development of fatty acid synthase inhibitors as anticancer agents

    Mini-Reviews in Medicinal Chemistry1970journal article

    View DOI
    35 cites

  20. Synthesis and biological evaluation of 2-(phenyl)-3H-benzo[d]imidazole-5-carboxylic acids and its methyl esters as potent anti-breast cancer agents

    Arabian Journal of Chemistry1970journal article

    View DOI
    35 cites

  21. Pyrimido[1¿,2¿:1,5]pyrazolo[3,4-b]quinolines: Novel compounds that reverse ABCG2-mediated resistance in cancer cells

    Cancer Letters1970journal article

    View DOI
    34 cites

  22. Targeting of tubulin polymerization and induction of mitotic blockage by Methyl 2-(5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) in human cervical cancer HeLa cell

    Journal of Experimental and Clinical Cancer Research1970journal article

    View DOI
    34 cites

  23. Synthesis, cytotoxic evaluation and in silico pharmacokinetic prediction of some benzo[a]phenazine-5-sulfonic acid derivatives

    Medicinal Chemistry1970journal article

    View DOI
    32 cites

  24. Lysinated Multiwalled Carbon Nanotubes with Carbohydrate Ligands as an Effective Nanocarrier for Targeted Doxorubicin Delivery to Breast Cancer Cells

    Molecules1970journal article

    View DOI
    29 cites

  25. Design, synthesis and molecular modelling studies of novel 3-acetamido-4-methyl benzoic acid derivatives as inhibitors of protein tyrosine phosphatase 1B

    European Journal of Medicinal Chemistry1970journal article

    View DOI
    29 cites

  26. Ligand-conjugated multiwalled carbon nanotubes for cancer targeted drug delivery

    2024

    View DOI
    28 cites

  27. lH-Pyrazolo[3,4-b]quinolin-3-amine derivatives inhibit growth of colon cancer cells via apoptosis and sub G1 cell cycle arrest

    Bioorganic and Medicinal Chemistry Letters1970journal article

    View DOI
    28 cites

  28. 2,3-Diaryl-3H-imidazo[4,5-b]pyridine derivatives as potential anticancer and anti-inflammatory agents

    Acta Pharmaceutica Sinica B1970journal article

    View DOI
    28 cites

  29. Multifunctional GQDs for receptor targeting, drug delivery, and bioimaging in pancreatic cancer

    Nanoscale1970journal article

    View DOI
    27 cites

  30. Design and discovery of silybin analogues as antiproliferative compounds using a ring disjunctive – Based, natural product lead optimization approach

    European Journal of Medicinal Chemistry1970journal article

    View DOI
    27 cites

  31. 3D QSAR of aminophenyl benzamide derivatives as histone deacetylase inhibitors

    Medicinal Chemistry1970journal article

    View DOI
    26 cites

  32. QSAR modelling of HIV-1 reverse transcriptase inhibition by benzoxazinones using a combination of P_VSA and pharmacophore feature descriptors

    Bioorganic and Medicinal Chemistry Letters1970journal article

    View DOI
    24 cites

  33. Design, synthesis and biological evaluation of some tetrazole acetamide derivatives as novel non-carboxylic PTP1B inhibitors

    Bioorganic Chemistry1970journal article

    View DOI
    24 cites

  34. Design, synthesis, cytotoxic evaluation, and QSAR study of some 6H-indolo[2,3-b]quinoxaline derivatives

    Journal of Enzyme Inhibition and Medicinal Chemistry1970journal article

    View DOI
    24 cites

  35. HM015k, a novel silybin derivative, multi-targets metastatic ovarian cancer cells and is safe in zebrafish toxicity studies

    Frontiers in Pharmacology1970journal article

    View DOI
    23 cites

  36. Optimization and kinetic studies on treatment of textile dye wastewater using Pleurotus floridanus

    2012

    View DOI
    22 cites

  37. Novel thienopyrimidine derivative, RP-010, induces β-catenin fragmentation and is efficacious against prostate cancer cells

    Cancers1970journal article

    View DOI
    19 cites

  38. The dopamine D<inf>3</inf> receptor antagonists PG01037, NGB2904, SB277011A, and U99194 reverse ABCG2 transporter-mediated drug resistance in cancer cell lines

    Cancer Letters1970journal article

    View DOI
    19 cites

  39. Synthesis, biological evaluation and molecular modelling studies of 4-anilinoquinazoline derivatives as protein kinase inhibitors

    Bioorganic and Medicinal Chemistry1970journal article

    View DOI
    19 cites

  40. Bax/Tubulin/Epithelial-mesenchymal pathways determine the efficacy of silybin analog HM015k in colorectal cancer cell growth and metastasis

    Frontiers in Pharmacology1970journal article

    View DOI
    18 cites

  41. Synthesis and biological evaluation of some N-(3-(1H-tetrazol-5-yl) phenyl)acetamide derivatives as novel non-carboxylic PTP1B inhibitors designed through bioisosteric modulation

    Bioorganic Chemistry1970journal article

    View DOI
    18 cites

  42. Mechanisms of the anti-tumor activity of Methyl 2-(-5-fluoro-2- hydroxyphenyl)-1 H-benzo[d]imidazole-5-carboxylate against breast cancer in vitro and in vivo

    Oncotarget1970journal article

    View DOI
    18 cites

  43. Stearidonic acid, a plant-based dietary fatty acid, enhances the chemosensitivity of canine lymphoid tumor cells

    Biochemical and Biophysical Research Communications1970journal article

    View DOI
    18 cites

  44. Localized delivery of cisplatin for the effective management of squamous cell carcinoma from protransfersome formulation

    Archives of Pharmacal Research1970journal article

    View DOI
    18 cites

  45. Simultaneous quantitative determination of zidovudine and nevirapine in human plasma using isocratic, reverse phase high performance liquid chromatography

    2009

    View DOI
    16 cites

  46. Synthesis, antifungal evaluation and in silico study of novel Schiff bases derived from 4-amino-5(3,5-dimethoxy-phenyl)-4H-1,2,4-triazol-3-thiol

    Arabian Journal of Chemistry1970journal article

    View DOI
    16 cites

  47. A new approach for PEGylation of dendrimers

    Bioorganic and Medicinal Chemistry Letters1970journal article

    View DOI
    16 cites

  48. QSAR analysis of some phthalimide analogues based inhibitors of HIV-1 integrase

    2007

    View DOI
    15 cites

  49. QSAR analysis of some phthalimide analogues based inhibitors of HIV-1 integrase

    Arkivoc1970journal article

    15 cites

  50. QSAR study of substituted 2-pyridinyl guanidines as selective urokinase-type plasminogen activator (uPA) inhibitors

    Journal of Enzyme Inhibition and Medicinal Chemistry1970journal article

    View DOI
    15 cites

  51. QSAR analysis of some 5-amino-2-mercapto-1,3,4-thiadiazole based inhibitors of matrix metalloproteinases and bacterial collagenase

    Bioorganic and Medicinal Chemistry Letters1970journal article

    View DOI
    15 cites

  52. Chewing gum as a drug delivery system

    2010

    14 cites

  53. Unravelling the potency of 4,5-diamino-4H-1,2,4 triazole-3-thiol derivatives for kinase inhibition using a rational approach

    New Journal of Chemistry1970journal article

    View DOI
    14 cites

  54. Comparative study of forced degradation behavior of prasugrel by uplc and hplc and the development of validated stability indicating assay method

    Journal of Liquid Chromatography and Related Technologies1970journal article

    View DOI
    14 cites

  55. Curcumin coating: a novel solution to mitigate inherent carbon nanotube toxicity

    2024

    View DOI
    12 cites

  56. Abacavir induces the transcriptional activity of YY1 and other oncogenic transcription factors in gastric cancer cells

    Antiviral Research1970journal article

    View DOI
    12 cites

  57. Cariprazine, a dopamine D<sub>2</sub>/D<sub>3</sub> receptor partial agonist, modulates ABCG2-mediated multidrug resistance in cancer

    Cancers1970journal article

    View DOI
    12 cites

  58. N-(1H-Pyrazol-3-yl)quinazolin-4-amines as a novel class of casein kinase 1d/e inhibitors: Synthesis, biological evaluation and molecular modeling studies

    Bioorganic and Medicinal Chemistry Letters1970journal article

    View DOI
    12 cites

  59. A validated UPLC method used for the determination of trandolapril and its degradation products as per ICH guidelines

    Current Pharmaceutical Analysis1970journal article

    View DOI
    12 cites

  60. Antiproliferative efficacy of n-(3-chloro-4-fluorophenyl)-6, 7-dimethoxyquinazolin-4-amine, dw-8, in colon cancer cells is mediated by intrinsic apoptosis

    Molecules1970journal article

    View DOI
    11 cites

  61. Design, synthesis and biological evaluation of novel arylidine- malononitrile derivatives as non-carboxylic inhibitors of protein tyrosine phosphatase 1B

    Medicinal Chemistry Research1970journal article

    View DOI
    11 cites

  62. The ICH guidance in practice: Stress degradation studies on irbesartan and development of a validated stability-indicating UPLC assay

    Acta Chromatographica1970journal article

    View DOI
    11 cites

  63. Fatty Acid Synthase (FASN): A Patent Review Since 2016-Present

    2023

    View DOI
    10 cites

  64. Multi-algorithm based machine learning and structural pattern studies for hERG ion channel blockers mediated cardiotoxicity prediction

    Chemometrics and Intelligent Laboratory Systems1970journal article

    View DOI
    10 cites

  65. IND-2, a Quinoline Derivative, Inhibits the Proliferation of Prostate Cancer Cells by Inducing Oxidative Stress, Apoptosis and Inhibiting Topoisomerase II

    Life1970journal article

    View DOI
    10 cites

  66. Quantitative structure-activity relationships of selective antagonists of glucagon receptor using QuaSAR descriptors

    Chemical and Pharmaceutical Bulletin1970journal article

    View DOI
    10 cites

  67. Medicinal Aspects of PTP1B Inhibitors as Anti-Breast Cancer Agents: An Overview

    Current Medicinal Chemistry2024journal article

    View DOI
    9 cites

  68. Design, synthesis, and anticancer activity of some novel 1H-benzo[d]imidazole-5-carboxamide derivatives as fatty acid synthase inhibitors

    2023

    View DOI
    9 cites

  69. Lead optimization of novel quinolone chalcone compounds by a structure–activity relationship (SAR) study to increase efficacy and metabolic stability

    Scientific Reports1970journal article

    View DOI
    9 cites

  70. A risk assessment approach: Qualification of a HVAC system in aseptic processing area using building management system

    Quality Assurance Journal1970journal article

    View DOI
    9 cites

  71. Endocytic highways: Navigating macropinocytosis and other endocytic routes for precision drug delivery

    2025

    View DOI
    8 cites

  72. New spectrophotometric methods applied to the simultaneous determination of diclofenac potassium and tizanidine

    2006

    View DOI
    8 cites

  73. Classification analysis of fatty acid synthase inhibitors using multialgorithms on topological descriptors and structural fingerprints

    Chemical Biology and Drug Design1970journal article

    View DOI
    8 cites

  74. Unravelling the Selectivity of 6,7-Dimethyl Quinoxaline Analogs for Kinase Inhibition: An Insight towards the Development of Alzheimer's Therapeutics

    Chemistry and Biodiversity1970journal article

    View DOI
    8 cites

  75. Use of lysinated multiwalled carbon nanotubes with carbohydrate ligands as a doxorubicin nanocarrier: A molecular dynamics analysis

    Carbon Trends2023journal article

    View DOI
    7 cites

  76. Development and validation of a RP-HPLC method for determination of citicoline monosodium in human plasma

    2011

    7 cites

  77. QSAR studies of cytotoxic acridine 5,7-diones : A comparative study using P-VSA descriptors and topological descriptors

    2007

    7 cites

  78. Novel 3-((2-chloroquinolin-3-yl)methylene)indolin-2-one derivatives produce anticancer efficacy in ovarian cancer in vitro

    Heliyon1970journal article

    View DOI
    7 cites

  79. Synthesis, in silico metabolic and toxicity prediction of some novel imidazolinones derivatives as potent anticonvulsant agents

    Journal of Enzyme Inhibition and Medicinal Chemistry1970journal article

    View DOI
    6 cites

  80. Anti-colorectal Cancer Activity of Quinazoline Derivatives: A ComprehensiveReview

    2023

    View DOI
    5 cites

  81. Design, synthesis and biological evaluation of 3-(2-(benzo[d]thiazol-2-ylthio)acetamido)benzoic acid derivatives as inhibitors of protein tyro-sine phosphatase 1b

    Letters in Drug Design and Discovery1970journal article

    View DOI
    5 cites

  82. Development and validation of a UV spectrophotometric method for simultaneous estimation of teneligliptin hydrobromide hydrate and pioglitazone hydrochloride in pharmaceutical dosage form

    2024

    View DOI
    4 cites

  83. In silico-guided discovery and in vitro validation of novel sugar-tethered lysinated carbon nanotubes for targeted drug delivery of doxorubicin

    Journal of Molecular Modeling2024journal article

    View DOI
    4 cites

  84. RP-HPLC method validation for fast extraction and quantification of Levonorgestrel drug from silicone based intrauterine device intended for in-process and finished formulation

    2021

    View DOI
    4 cites

  85. Analysis of diabetic retinopathy using naive bayes classifier technique

    2018

    View DOI
    4 cites

  86. Modeling VEGFR kinase inhibition of aminopyrazolopyridine urea derivatives using topological and physicochemical descriptors: A quantitative structure activity analysis study

    Medicinal Chemistry Research1970journal article

    View DOI
    4 cites

  87. Substituent Orchestration in Dimethylquinoxaline Derivatives: A Tool for Fishing Out Appropriate CDK5 Inhibitors as Potential Therapeutics for Alzheimer's

    Chemistry and Biodiversity1970journal article

    View DOI
    4 cites

  88. Design, synthesis, and pharmacological evaluation of heteroaryl thiol-linked kojic acid derivatives as a novel class of acetylcholinesterase inhibitors for Alzheimer’s disease therapy

    2025

    View DOI
    3 cites

  89. Theoretical insights into PtSSe–SnSSe heterostructures for renewable energy applications

    2025

    View DOI
    3 cites

  90. Design and Implementation of Biomedical Device for Monitoring Fetal ECG

    2020

    View DOI
    3 cites

  91. Column studies on sorption of Cr (VI) from aqueous and electroplating wastewater using acid-treated marine brown algae <i>Sargassum myriocystum</i>

    2019

    View DOI
    3 cites

  92. Synthesis, characterization and cytotoxicity studies of CuO nanoparticles by using Gymnema sylvestre leaf extracts

    2016

    View DOI
    3 cites

  93. Synthesis and evaluation of some amino acid conjugates of pirprofen

    Biomedicine and Preventive Nutrition1970journal article

    View DOI
    3 cites

  94. Synthesis and evaluation of some amino acid conjugates of suprofen

    Biomedicine and Preventive Nutrition1970journal article

    View DOI
    3 cites

  95. QSAR analysis of HIV-1 reverse transcriptase inhibitory 5-alkyl-2- [(aryl and alkyloxylcarbonylmethyl) thio]-6- (1-napthylmethyl) pyrimidin-4 (3H)-ones

    International Journal of Virology1970journal article

    View DOI
    3 cites

  96. Quantitative structure activity relationship studies of piperazinyl phenylalanine derivatives as VLA-4/VCAM-1 inhibitors

    Medicinal Chemistry1970journal article

    View DOI
    3 cites

  97. QSAR study on hetaryl imidazoles: A novel dual inhibitor of VEGF receptors I and II

    Medicinal Chemistry1970journal article

    View DOI
    2 cites

  98. Analysis of surface area features of structurally diverse molecules for Bcr/Abl kinase inhibitory activity and antiproliferative activity

    Medicinal Chemistry Research1970journal article

    View DOI
    2 cites

  99. QSAR study on N-(aryl)-4-(azolylethyl) thiazole-5-carboxamides: Novel potent inhibitors of VEGF receptors I and II

    Medicinal Chemistry1970journal article

    View DOI
    2 cites

  100. Antiplasmodial metabolites from Baccharoides anthelmintica seeds: In vitro and in silico profiling

    Journal of Ethnopharmacology2026journal article

    View DOI
    1 cites

  101. The hidden hand of endoplasmic reticulum stress in anticancer drug resistance

    2025

    View DOI
    1 cites

  102. Future prospects of targeted drug delivery

    2025

    View DOI
    1 cites

  103. Targeted Delivery of Doxorubicin to Breast Cancer Cells by Multiwalled Carbon Nanotubes Functionalized with Lysine via 1,3-Dipolar Cycloaddition and Conjugation with Sugar Moieties

    2022

    View DOI
    1 cites

  104. A Study on Impact of Store Satisfaction, Merchandise Quality, and Service Quality of Store on Store Loyalty with Reference to Mom &amp; Me Store Anna Nagar

    2012

    View DOI
    1 cites

  105. Determination of salmeterol xinafoate and its degradation products according to ICH guidelines with use of UPLC technique

    2011

    1 cites

  106. RP-HPLC method for simultaneous estimation of amlodipine and valsartan in tablet formulation and validation as per ICH guidelines

    2011

    1 cites

  107. Computer-Assisted Drug Design: A Toolbox for Novel Tau Kinase Inhibitors and Its Implications in Alzheimer’s Disease

    Neuromethods1970book chapter

    View DOI
    1 cites

  108. Targeting Angiotensin-converting Enzyme 2 (ACE2) for the Discovery of Anticoronaviral Drugs

    Coronaviruses1970journal article

    View DOI
    1 cites

  109. Virtual screening based discovery of PTP1B inhibitors and their biological evaluations

    Letters in Drug Design and Discovery1970journal article

    View DOI
    1 cites

  110. The Novel Thienopyrimidine Derivative, RP-010, Produces Its Efficacy in Prostate Cancer Cells by Inducing the Fragmentation of β-catenin

    1970other

    View DOI
    1 cites

  111. Quantitative structure activity analysis of 2-alkoxydihydrocinnamates as PPARα/γ dual agonist

    Medicinal Chemistry1970journal article

    View DOI
    1 cites

  112. Vacuolization as a Novel Approach to Cancer Therapy

    2026

    View DOI
    0 cites

  113. Design, synthesis, and in-vitro evaluation of 2-(heteroarylthio)acetamido-1H-benzo[d]imidazole derivatives as PTP1B inhibitors for the treatment of type 2 diabetes

    2026

    View DOI
    0 cites

  114. Abstract LB315: Targeting endolysosomal trafficking to overcome paclitaxel resistance in triple-negative breast cancer

    2026

    View DOI
    0 cites

  115. Validated Green UV Spectrophotometric Approach for the Simultaneous Estimation of Torsemide and Eplerenone in Pharmaceutical Formulationusing Green Assessment Tools

    2026

    View DOI
    0 cites

  116. The Therapeutic Promise of Kojic Acid: A Comprehensive Review

    2026

    View DOI
    0 cites

  117. Investigation of plant-derived compounds as potent inhibitors of casein kinase-1 alpha through computational analysis and molecular dynamic simulations

    2026

    View DOI
    0 cites

  118. Synthesis, Biological evaluation, and computational study of 2-((2-oxo-2-(arylamino)ethyl)thio)-1H-benzo[d]imidazole-5-carboxylic acids as PTP1B inhibitors for the treatment of type 2 diabetes

    2026

    View DOI
    0 cites

  119. Correction: Updated insights on ASK1 signaling: mechanisms, regulation, and therapeutic potential in diseases

    2025

    View DOI
    0 cites

  120. Patent landscape in hydroxamic acid-based HDAC inhibitors (2020–2024): structure–activity relationships and mechanistic insights

    2025

    View DOI
    0 cites

  121. Identification and Mechanistic Profiling of Indolin‐2‐One Derivatives That Induce ROS‐Driven Intrinsic Apoptosis in Prostate and Colorectal Cancer Cells

    2025

    View DOI
    0 cites

  122. Novel macropinocytosis inducers selectively modulate intracellular delivery of small and macromolecules in cancer cells

    2025

    View DOI
    0 cites

  123. Design, synthesis and biological evaluation of 2-phenylquinoxaline carbonyl piperazine derivatives as novel FASN inhibitors with anticancer activity

    2025

    View DOI
    0 cites

  124. Validated Novel Green Uv Spectrophotometric Method for the Simultaneous Estimation of Torsemide and Eplerenone in Pharmaceutical Formulation

    2025

    View DOI
    0 cites

  125. CRISPR plants for studying signal transduction pathways: Methods and applications

    2025

    View DOI
    0 cites

  126. Contributors

    2025

    View DOI
    0 cites

  127. Ligand based analysis of the solubility of drugs using in silico techniques

    2025

    View DOI
    0 cites

  128. Machine learning-based analysis on retention time of pesticides for eco-friendly and cost-effective analytical method development

    2025

    View DOI
    0 cites

  129. Thienopyrimidine derivatives TPH104c and TPH104m induce JNK/BNIP3-mediated mitochondrial dysfunction and promotes mitophagy in triple-negative breast cancer

    2025

    View DOI
    0 cites

  130. Chapter 15 Hydrogen burners for effective utilization of hydrogen as the future fuel

    2024

    View DOI
    0 cites

  131. List of contributors

    2024

    View DOI
    0 cites

  132. Exploring material and metals for antimicrobial nanocoatings

    2024

    View DOI
    0 cites

  133. Systemized and Effective Methodologies of Converting Worn Naphtha Plastic into Combustible Fuels

    2024

    View DOI
    0 cites

  134. Abstract 4974: Development of novel pyrimido-pyrazolo-quinolone derivative, IND-2 as multi-targeted inhibitor for the treatment of prostate cancer

    2023

    View DOI
    0 cites

  135. Design, Synthesis and Biological Evaluation of Novel 1H-benzo[d]imidazole Derivatives as Fatty Acid Synthase (FASN) Inhibitors for Cancer Treatment

    2022

    View DOI
    0 cites

  136. Molecular Dynamic Simulations-Based Conformational Analysis and Binding Study of CP-225917 on Farnesyl Transferase Enzyme

    2022

    View DOI
    0 cites

  137. Abstract 5656: Design and development of novel anticancer dimethoxyquinazoline-4-amine analog, DW-8, against colorectal cancer

    2022

    View DOI
    0 cites

  138. Synthesis, biological evaluation and molecular docking studies of 4-arylidene-2-phenyloxazol-5(4H)-one derivatives as inhibitors of dual-specificity tyrosine phosphorylation-regulated kinases and Cdc2-like kinases

    2021

    View DOI
    0 cites

  139. Lead optimization of novel quinolone chalcone compounds by a structure-activity relationship (SAR) study to increase efficacy and metabolic stability

    2021

    View DOI
    0 cites

  140. Contributors

    2019

    View DOI
    0 cites

  141. Additional file 2: Figure S2. of Targeting of tubulin polymerization and induction of mitotic blockage by Methyl 2-(5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) in human cervical cancer HeLa cell

    2016

    View DOI
    0 cites

  142. Additional file 1: Figure S1. of Targeting of tubulin polymerization and induction of mitotic blockage by Methyl 2-(5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) in human cervical cancer HeLa cell

    2016

    View DOI
    0 cites

  143. Synthesis, characterization and biological evaluation of N-(5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-yl)-4-nitrobenzamide derivatives

    2015

    0 cites

  144. Study of forced degradation behaviour of eprosartan mesylate and development of validated stability indicating assay method by UPLC

    2011

    0 cites

  145. RP-HPLC method for estimation and stability study of drotaverine HCl as per ICH guidelines

    2011

    0 cites

  146. A simulation solution for improvement of quality and productivity in failure textile industry

    2010

    0 cites

  147. A QSAR analysis of some amino substituted Pyrido[3,2-b]pyrazinones as potent and selective PDE-5 inhibitors

    2010

    View DOI
    0 cites

  148. Stability-Indicating Assay Method for Estimation of Olmesartan Medoxomil and its Metabolite

    Journal of Liquid Chromatography &amp; Related Technologies2009journal article

    View DOI
    0 cites

  149. A novel dialkylamino-functionalized chalcone, DML6, inhibits cervical cancer cell proliferation, in vitro, via induction of oxidative stress, intrinsic apoptosis and mitotic catastrophe

    Molecules1970journal article

    View DOI
    0 cites

  150. Lead optimization of novel quinolone chalcone compounds by a structure-activity relationship (SAR) study to increase efficacy and metabolic stability

    ResearchSquare1970other

    View DOI
    0 cites

  151. In search of novel tau kinase inhibitors and their role in alzheimer’s therapy

    A Closer Look at Kinase Inhibition1970book chapter

    0 cites

  152. A new simple and rapid validated RP-HPLC method for determination of ziprasidone in ziprasidone capsules

    Journal of Saudi Chemical Society1970journal article

    View DOI
    0 cites

  153. Synthesis, characterization and cytotoxicity studies of CuO nanoparticles by using Gymnema sylvestre leaf extracts

    Journal of the Indian Chemical Society1970journal article

    0 cites

  154. Advances in chalcones with anticancer activities

    Recent Patents on Anti-Cancer Drug Discovery1970journal article

    0 cites

  155. Advances in chalcones with anticancer activities

    Recent Patents on Anti-Cancer Drug Discovery1970journal article

    0 cites

  156. Synthesis, characterization and biological evaluation of N-(5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-yl)-4-nitrobenzamide derivatives

    Der Pharma Chemica1970journal article

    0 cites

  157. Synthesis, characterization and biological evaluation of N-(5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-yl)-4-nitrobenzamide derivatives

    Der Pharma Chemica1970journal article

    0 cites

  158. Nimesulide and celecoxib inhibits multiple oncogenic pathways in gastric cancer cells

    Journal of Cancer Science and Therapy1970journal article

    View DOI
    0 cites

  159. Determination of salmeterol xinafoate and its degradation products according to ICH guidelines with use of UPLC technique

    Latin American Journal of Pharmacy1970journal article

    0 cites

  160. Development and validation of a RP-HPLC method for determination of citicoline monosodium in human plasma

    Latin American Journal of Pharmacy1970journal article

    0 cites

  161. RP-HPLC method for estimation and stability study of drotaverine HCl as per ICH guidelines

    Latin American Journal of Pharmacy1970journal article

    0 cites

  162. RP-HPLC method for simultaneous estimation of amlodipine and valsartan in tablet formulation and validation as per ICH guidelines

    Latin American Journal of Pharmacy1970journal article

    0 cites

  163. Study of forced degradation behaviour of eprosartan mesylate and development of validated stability indicating assay method by UPLC

    Latin American Journal of Pharmacy1970journal article

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  164. Synthesis of some coumarinyl chalcones and their antiproliferative activity against breast cancer cell lines

    Letters in Drug Design and Discovery1970journal article

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  165. Design, synthesis and characterization of novel 1,3,4-oxadiazole dimers from benzoic acids

    International Journal of ChemTech Research1970journal article

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  166. Simultaneous quantitative determination of zidovudine and nevirapine in human plasma using isocratic, reverse phase high performance liquid chromatography

    Tropical Journal of Pharmaceutical Research1970journal article

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  167. Quantitative structure activity relationship analysis of some diarylsulphonylurea derivatives as tubulin binding agents

    International Journal of Cancer Research1970journal article

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  168. QSAR analysis of HIV-1 reverse transcriptase inhibitory 5-alkyl-2-[(aryl and alkyloxycarbonlmethyl) thio]-6- (1-napthylmethyl) pyrimidin-4 (3H)-ones

    International Journal of Virology1970journal article

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  169. QSAR studies of cytotoxic acridine 5,7-diones: A comparative study using P-VSA descriptors and topological descriptors

    Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry1970journal article

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  170. New spectrophotometric methods applied to the simultaneous determination of diclofenac potassium and tizanidine

    Indian Journal of Pharmaceutical Sciences1970journal article

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  171. Simultaneous spectrophotometry methods for the estimation of nimesulide and tizanidine in a tablet dosage form

    Indian Journal of Pharmaceutical Sciences1970journal article

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