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Jayant Sindhu

University of DelhiIN
ORCID0000-0003-0207-0662
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28

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Citations
2,521

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Publications
100

About

Jayant Sindhu is a researcher at the University of Delhi. With over 100 publications spanning nearly six decades, from 1970 to 2025, his work focuses on organic synthesis and medicinal chemistry. Sindhu's research has explored various areas, including CO2 capture, enzyme inhibitors, and photophysical properties of conjugated molecules.

Research areas

  • Chemistry
  • Combinatorial chemistry
  • Stereochemistry
  • Organic chemistry
  • Biochemistry

Publications (100)

Sorted by most cited.

  1. Quasi-SMILES as a basis for the development of QSPR models to predict the CO2 capture capacity of deep eutectic solvents using correlation intensity index and consensus modelling

    Fuel1970journal article

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    24 cites

  2. QSAR study of tetrahydropteridin derivatives as polo-like kinase 1(PLK1) Inhibitors with molecular docking and dynamics study

    SAR and QSAR in Environmental Research1970journal article

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    9 cites

  3. Design, Microwave Assisted Synthesis, and Photophysical Properties of an Extensive Library of Conjugated Blue Emissive 4,6‐diaryl‐3‐cyano‐2‐pyridones

    ChemistrySelect2025journal article

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    0 cites

  4. Synthesis, C-N/N-N bond conformational analysis and evaluation of naphtho[2,3-d][1,2,3]triazole-4,9-dione tethered N-acyl hydrazones as α-amylase inhibitors: Insights from molecular modeling and ADMET analysis

    Journal of Molecular Structure2025journal article

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    0 cites

  5. Multicomponent Synthesis of 2,4,5-Trisubstituted Thiazoles Using a Sustainable Carbonaceous Catalyst and Assessment of Its Herbicidal and Antibacterial Potential

    Journal of Agricultural and Food Chemistry2024journal article

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    0 cites

  6. Unraveling the ability of electronically diverse 9H-carbazoles as potential fluorophores in cellular imaging applications with BSA binding affinities

    Journal of Photochemistry and Photobiology A: Chemistry2024journal article

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    0 cites

  7. Naphthoquinone fused diazepines targeting hyperamylasemia: potential therapeutic agents for diabetes and cancer

    Future Medicinal Chemistry2024journal article

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    0 cites

  8. Design, Synthesis, Nematicidal Evaluation, and Molecular Docking Study of Pyrano[3,2-c]pyridones against Meloidogyne incognita

    Journal of Agricultural and Food Chemistry2024journal article

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    0 cites

  9. Unraveling biological disparities in configurational isomers of pyrazolyl-dihydrofurans using in vitro, DFT and in silico approach

    Journal of Molecular Structure2024journal article

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    0 cites

  10. Exploring allelochemicals for cleaner and sustainable agriculture: A bibliometric review on research trends, challenges and future prospective

    Physiologia Plantarum2024journal article

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    0 cites

  11. Analysis of good and bad fingerprint for identification of NIR based optical frameworks using Monte Carlo method

    Microchemical Journal1970journal article

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  12. Computational and optoelectronic investigations of red-emissive europium (III) β-diketonate with n-donor ligands for display applications

    Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy1970journal article

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    0 cites

  13. Design and photophysical characterization of dinuclear lanthanide complexes incorporating spacer ligands along with their mononuclear analogues: A comparative study

    Optical Materials1970journal article

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    0 cites

  14. Design, synthesis and antimicrobial activities of 1,2,3-triazole hybrids with amine-ester functionality

    Medicinal Chemistry Research1970journal article

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    0 cites

  15. Diastereomeric pure pyrazolyl-indolyl dihydrofurans: Unveiling isomeric selectivity in antibacterial action <i>via in vitro</i> and <i>in silico insights</i>

    Bioorganic & Medicinal Chemistry Letters1970journal article

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    0 cites

  16. Divulging indolium inspired cyanide sensors: Did it win the throne?

    Coordination Chemistry Reviews1970journal article

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    0 cites

  17. Enhancement in photophysical properties of octacoordinated Dy(III) complexes via energy transfer from photosensitizing ligands

    Optical Materials1970journal article

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  18. Examination of the spectroscopic characteristics of bright green emitting, octa coordinated luminescent terbium (III) complexes

    Polyhedron1970journal article

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  19. Green emissive Tb(III) complexes based on photosensitizing antenna: Synthesis and optoelectronic analysis

    Materials Science in Semiconductor Processing1970journal article

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    0 cites

  20. Metal-Free Synthesis of 2-Aminothiazole Functionalized Imidazo[1,2-a]pyridines as Antibacterial Agents

    Indian Journal of Heterocyclic Chemistry1970journal article

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  21. NUV-excitation Dy(III) complexes: Synthesis, structural study and impact of secondary ligands on optoelectronic properties

    Journal of Molecular Structure1970journal article

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  22. Photophysical analysis and Judd-Ofelt calculation of Eu (III) complexes: Influence of various neutral ligands on luminescent properties

    Journal of Molecular Structure1970journal article

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    0 cites

  23. Precisely designed NIR based conjugated framework as a solid state emitter for selective recognition of cyanide ion in solid state and cancer cells

    Journal of Photochemistry and Photobiology A: Chemistry1970journal article

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    0 cites

  24. Pushing Boundaries: What's Next in Metal-Free C-H Functionalization for Sulfenylation?

    Topics in Current Chemistry (Cham)1970journal article

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    0 cites

  25. Pyrano[2,3-<i>c</i>]pyrazole fused spirooxindole-linked 1,2,3-triazoles as antioxidant agents: Exploring their utility in the development of antidiabetic drugs via inhibition of α-amylase and DPP4 activity

    Bioorganic Chemistry1970journal article

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    0 cites

  26. Quinoxaline-linked<i> N</i>-acyl hydrazine: A "<i> turn-off</i> ' fluorescent probe for the selective recognition of Fe 3+in real water samples

    Journal of Photochemistry and Photobiology A: Chemistry1970journal article

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    0 cites

  27. Rationally designed C-3 sulfenylated 2-phenyl-4H-pyrido[1,2-a] pyrimidin-4-one based fluorescent probe for recognition of Fe3+

    Journal of Molecular Structure1970journal article

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    0 cites

  28. Rationally designed dual channel reversible probe for cyanide recognition in aqueous medium with solid-state sensing abilities

    Journal of Photochemistry and Photobiology A: Chemistry1970journal article

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    0 cites

  29. Real time monitoring of nerve agent mimics: Novel solid state emitter for enhanced precision and reliability

    Journal of Hazardous Materials1970journal article

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    0 cites

  30. Samarium (III) complexes with tunable luminescence: efficient sensitization and semiconducting properties for optoelectronic devices

    Journal of Materials Science: Materials in Electronics1970journal article

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    0 cites

  31. Schiff base ligand: A colorimetric approach for tungsten and carbonate detection with insights into BSA binding studies

    Inorganic Chemistry Communications1970journal article

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    0 cites

  32. Structural attributes driving Amax towards NIR region: A QSPR approach

    Chemometrics and Intelligent Laboratory Systems1970journal article

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    0 cites

  33. Synthesis and photoluminescent studies of orange-red emissive samarium (III) complexes with 1,1,1-trifluoro-5,5-dimethyl-2,4-hexanedione and 2,2′-bipyridine and its distinctive analogous

    Inorganica Chimica Acta1970journal article

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    0 cites

  34. Synthesis of thiazolidine-2,4-dione tethered 1,2,3-triazoles as α-amylase inhibitors: In vitro approach coupled with QSAR, molecular docking, molecular dynamics and ADMET studies

    European Journal of Medicinal Chemistry1970journal article

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    0 cites

  35. TBHP: A Sustainable Alternative For Carbon-Oxygen Bond Formation

    European Journal of Organic Chemistry1970journal article

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    0 cites

  36. 5-Hydroxydibenzo[a,i]phenazine-8,13-dione: A selective and sensitive colorimetric and fluorescent<i> 'turn-off'</i> sensor for iodide ion

    Journal of Molecular Structure1970journal article

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    0 cites

  37. CORAL: probing the structural requirements for α-amylase inhibition activity of 5-(3-arylallylidene)-2-(arylimino)thiazolidin-4-one derivatives based on QSAR with correlation intensity index, molecular docking, molecular dynamics, and ADMET studies

    Journal of Biomolecular Structure and Dynamics1970journal article

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    0 cites

  38. Design and Development of COX-II Inhibitors: Current Scenario and Future Perspective

    ACS Omega1970journal article

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    0 cites

  39. Design, synthesis, spectroscopic characterization, single crystal X-ray analysis, in vitro α-amylase inhibition assay, DPPH free radical evaluation and computational studies of naphtho[2,3-d]imidazole-4,9-dione appended 1,2,3-triazoles

    European Journal of Medicinal Chemistry1970journal article

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    0 cites

  40. Development of thiazole-appended novel hydrazones as a new class of a-amylase inhibitors with anticancer assets: an<i> in silico </i>and<i> in vitro</i> approach

    RSC Medicinal Chemistry1970journal article

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    0 cites

  41. Electro-organic synthesis of C-5 sulfenylated amino uracils: Optimization and exploring topoisomerase-I based anti-cancer profile

    Bioorganic Chemistry1970journal article

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    0 cites

  42. Indolizine: A Promising Framework for Developing a Diverse Array of C-H Functionalized Hybrids

    ChemistrySelect1970journal article

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    0 cites

  43. Mixed ligand approach for novel hydrazide copper(II) complexes: Structural aspects, theoretical investigation and their biological evaluation

    Applied Organometallic Chemistry1970journal article

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    0 cites

  44. Parsing structural fragments of thiazolidin-4-one based ?-amylase inhibitors: A combined approach employing<i> in</i><i> vitro</i> colorimetric screening and GA-MLR based QSAR modelling supported by molecular docking, molecular dynamics simulation and ADMET studies

    Computers in Biology and Medicine1970journal article

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    0 cites

  45. Precisely designed oxazolonaphthoimidazo[1,2-a]pyridine-based sensor for the detection of Fe3+and DCP with cell imaging application

    Journal of Photochemistry and Photobiology A: Chemistry1970journal article

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    0 cites

  46. QSAR analysis for pyrimidine and pyridine derivatives as RIPK2 (receptor interacting protein kinase 2) inhibitors

    Journal of the Indian Chemical Society1970journal article

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    0 cites

  47. Quantitative structure activity relationship studies of androgen receptor binding affinity of endocrine disruptor chemicals with index of ideality of correlation, their molecular docking, molecular dynamics and ADME studies

    Journal of Biomolecular Structure and Dynamics1970journal article

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    0 cites

  48. Quinoxaline-derived "turn-off" fluorescent sensor for the selective detection of Fe3+: Synthesis, spectroscopic analysis, BSA binding and computational studies

    Journal of Molecular Structure1970journal article

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    0 cites

  49. Rationally designed novel phenazine based chemosensor with real time Hg<SUP>2+</SUP> sensing application

    Journal of Molecular Structure1970journal article

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    0 cites

  50. Synthesis, Characterization and Evaluation of Antimicrobial Activity, Phytotoxicity, Molecular Docking & Dynamic Simulations of Benzothiazole Functionalized C-C Linked Pyrazolyl-Thiazoles

    ChemistrySelect1970journal article

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    0 cites

  51. Thiazolidine-2,4-dione framework containing spiropyrrolidine-oxindole and 1,2,3-triazole scaffold: synthesis, in vitro a-amylase inhibition and in s<i>ilico</i> studies

    New Journal of Chemistry1970journal article

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    0 cites

  52. Thiazolidinedione-triazole conjugates: design, synthesis and probing of the α-amylase inhibitory potential

    Future Medicinal Chemistry1970journal article

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    0 cites

  53. Urease Inhibition and Structure-Activity Relationship Study of Thiazolidinone-, Triazole-, and Benzothiazole-Based Heterocyclic Derivatives: A Focus Review

    ChemistrySelect1970journal article

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    0 cites

  54. α-Amylase Inhibitors Based on Thiazolidinone Skeleton: A Promising Approach in Diabetes Management

    ChemistrySelect1970journal article

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    0 cites

  55. α-amylase inhibition and <i>in silico</i> studies of novel naphtho[2,3-d]imidazole-4,9-dione linked <i>N</i>-acyl hydrazones

    Future Medicinal Chemistry1970journal article

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  56. A comprehensive review on synthesis, biological profile and photophysical studies of heterocyclic compounds derived from 2,3-diamino-1,4-naphthoquinone

    Journal of Molecular Structure1970journal article

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  57. Antimicrobial evaluation and QSAR studies of 3,6-disubstituted-11H-benzo [5,6][1,4]thiazino[3,4-a]isoindol-11-ones

    European Journal of Medicinal Chemistry Reports1970journal article

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  58. Electro-organic synthesis: an environmentally benign alternative for heterocycle synthesis

    Organic & Biomolecular Chemistry1970journal article

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  59. Electro-organic synthesis: an environmentally benign alternative for heterocycle synthesis (vol 20, pg 5163, 2022)

    Organic & Biomolecular Chemistry1970journal article

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    0 cites

  60. Monte Carlo based QSGFEAR: prediction of Gibb's free energy of activation at different temperatures using SMILES based descriptors

    New Journal of Chemistry1970journal article

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    0 cites

  61. Quantitative structure activity relationship studies of novel hydrazone derivatives as α-amylase inhibitors with index of ideality of correlation

    Journal of Biomolecular Structure and Dynamics1970journal article

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    0 cites

  62. Sonochemical Protocols for Heterocyclic Synthesis: A Representative Review

    Topics in Current Chemistry (Cham)1970journal article

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    0 cites

  63. Structural Diversity of D-Alanine: D-Alanine Ligase and Its Exploration in Development of Antibacterial Agents Against the Multi-Variant Bacterial Infections

    ChemistrySelect1970journal article

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    0 cites

  64. Synthesis and exploration of configurational dynamics in equilibrating <i>E</i>/<i>Z</i> 2-aryliminothiazolidin-4-ones using NMR and estimation of thermodynamic parameters

    New Journal of Chemistry1970journal article

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  65. Unravelling the thermodynamics and binding interactions of bovine serum albumin (BSA) with thiazole based carbohydrazide: Multi-spectroscopic, DFT and molecular dynamics approach

    Journal of Molecular Structure1970journal article

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    0 cites

  66. <i>In-silico</i> identification of fingerprint of pyrazolyl sulfonamide responsible for inhibition of <i>N</i>-myristoyltransferase using Monte Carlo method with index of ideality of correlation

    Journal of Biomolecular Structure and Dynamics1970journal article

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  67. Excited-State Intramolecular Hydrogen-Bonding-Assisted Restricted Rotation: A Mechanism for Monitoring Intracellular Viscosity and Distinguishing Malignant, Differentiating, and Apoptotic Cancer Cells

    ACS Applied Bio Materials1970journal article

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    0 cites

  68. Experimental and Computational Validation of Structural Features and BSA Binding Tendency of 5-Hydroxy-5-trifluoromethyl-3-arylpyrazolines**

    ChemistrySelect1970journal article

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  69. Exploration of synthesis, structural aspects, DFT studies and bio-efficacy of some new DHA-benzohydrazide based copper(II) complexes

    Journal of Molecular Structure1970journal article

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  70. Exploring biological efficacy of novel benzothiazole linked 2,5-disubstituted-1,3,4-oxadiazole hybrids as efficient α-amylase inhibitors: Synthesis, characterization, inhibition, molecular docking, molecular dynamics and Monte Carlo based QSAR studies

    Computers in Biology and Medicine1970journal article

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    0 cites

  71. Recent efforts for drug identification from phytochemicals against SARS-CoV-2: Exploration of the chemical space to identify druggable leads

    Food and Chemical Toxicology1970journal article

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  72. Solid-Supported Materials-Based Synthesis of 2-Substituted Benzothiazoles: Recent Developments and Sanguine Future

    ChemistrySelect1970journal article

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    0 cites

  73. Synthesis, Crystal structure and DFT studies of Polyfunctionalized Alkenes: A transition Metal-Free C(<i>sp</i><SUP>2</SUP>)-H Sulfenylation of electron deficient Alkyne

    Journal of Molecular Structure1970journal article

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  74. Synthesis, molecular docking and QSAR study of thiazole clubbed pyrazole hybrid as α-amylase inhibitor

    Journal of Biomolecular Structure and Dynamics1970journal article

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  75. Synthesis, structural and pharmacological exploration of 2-(3, 5-dimethyl-1<i>H</i>-pyrazol-1-yl)-acetophenone oximes and their silver complexes

    Polyhedron1970journal article

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  76. Transition Metal-Free Sulfenylation of C-H Bonds for C-S Bond Formation in Recent Years: Mechanistic Approach and Promising Future

    ChemistrySelect1970journal article

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  77. Transition metal-free C-3 functionalization of quinoxalin-2(1<i>H</i>)-ones: recent advances and sanguine future

    New Journal of Chemistry1970journal article

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  78. Eco-friendly Preparations of Heterocycles Using Fruit Juices as Catalysts: A Review

    Organic Preparations and Procedures International1970journal article

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  79. Synthesis, Crystal and DFT studies of Zn/Co complexes of Dehydroacetic acid using ligand exchange approach

    Inorganic Chemistry Communications1970journal article

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  80. Thiazolidine-4-one clubbed pyrazoles hybrids: Potent α-amylase and α-glucosidase inhibitors with NLO properties

    Journal of Heterocyclic Chemistry1970journal article

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  81. Crystal structure, Hirshfeld surface, DFT and BSA binding studies of dihydropyrazole-1-thiocarboxamides

    Journal of Molecular Structure1970journal article

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  82. Design and development of novel focal adhesion kinase (FAK) inhibitors using Monte Carlo method with index of ideality of correlation to validate QSAR

    SAR and QSAR in Environmental Research1970journal article

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  83. Development of an off-on selective fluorescent sensor for the detection of Fe<SUP>3+</SUP> ions based on Schiff base and its Hirshfeld surface and DFT studies

    Journal of Molecular Liquids1970journal article

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  84. Disaggregation-induced ESIPT: a novel approach towards development of sensors for hyperglycemic condition

    New Journal of Chemistry1970journal article

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  85. In silico design of diacylglycerol acyltransferase-1 (DGAT1) inhibitors based on SMILES descriptors using Monte-Carlo method

    SAR and QSAR in Environmental Research1970journal article

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  86. QSAR Models for Nitrogen Containing Monophosphonate and Bisphosphonate Derivatives as Human Farnesyl Pyrophosphate Synthase Inhibitors Based on Monte Carlo Method

    Drug Research1970journal article

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  87. Silica-supported ceric ammonium nitrate (CAN): a simple, mild and solid-supported reagent for quickest oxidative aromatization of Hantzsch 1,4-dihydropyridines

    Chemical Papers1970journal article

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  88. Design, synthesis, DFT, docking studies and ADME prediction of some new coumarinyl linked pyrazolylthiazoles: Potential standalone or adjuvant antimicrobial agents

    Plos One1970journal article

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  89. Design, synthesis, conformational and molecular docking study of some novel acyl hydrazone based molecular hybrids as antimalarial and antimicrobial agents (vol 11, 115, 2017)

    Chemistry Central Journal1970journal article

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  90. Design, synthesis, conformational and molecular docking study of some novel acyl hydrazone based molecular hybrids as antimalarial and antimicrobial agents

    Chemistry Central Journal1970journal article

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  91. Synthesis of novel inhibitors of α-amylase based on the thiazolidine-4-one skeleton containing a pyrazole moiety and their configurational studies

    MedChemComm1970journal article

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  92. Cathepsin B, H and L inhibitors as cell proliferating agents: design, synthesis, computational and pharmacological studies of some novel 2-(2-naphthoyl)-6,6-dimethyl-3-aryl-2,3,6,7-tetrahydrobenzofuran-4(5<i>H</i>)-ones

    RSC Advances1970journal article

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  93. Synthesis and biological evaluation of some functionalized 1<i>H</i>-1,2,3-triazole tethered pyrazolo[3,4-<i>b</i>]pyridin-6(7<i>H</i>)-ones as antimicrobial and apoptosis inducing agents

    Medicinal Chemistry Research1970journal article

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  94. An efficient, green synthesis of novel regioselective and stereoselective indan-1,3-dione grafted spirooxindolopyrrolizidine linked 1,2,3-triazoles <i>via</i> a one-pot five-component condensation using PEG-400

    RSC Advances1970journal article

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  95. EFFICIENT GREEN APPROACH FOR THE SYNTHESIS OF SPIRO[INDOLINE-3,4′-PYRAZOLO[3,4-<i>b</i>]QUINOLINE] DIONES USING [NMP]H<sub>2</sub>PO<sub>4</sub> AND SOLVATOCHROMIC AND pH STUDIES

    Synthetic Communications1970journal article

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  96. EFFICIENT SYNTHESIS OF SPIRO[DIINDENOPYRIDINE-INDOLINE]TRIONES CATALYZED BY PEG-OSO<sub>3</sub>H-H<sub>2</sub>O AND [NMP]H<sub>2</sub>PO<sub>4</sub>

    Synthetic Communications1970journal article

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  97. Identifications of good and bad structural fragments of hydrazone/2,5-disubstituted-1,3,4-oxadiazole hybrids with correlation intensity index and consensus modelling using Monte Carlo based QSAR studies, their molecular docking and ADME analysis

    SAR and QSAR in Environmental Research1970journal article

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  98. AIE active Schiff base derived Pd(II) complex as a ratiometric sensor for fluoride ion

    Inorganica Chimica Acta1970journal article

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  99. Multi-faceted exploration of amide-amine tethered 1,2,3-triazole conjugates as antimicrobial agents using synthetic,<i> in</i><i> vitro</i> and<i> in</i><i> silico</i> approach

    Journal of Molecular Structure1970journal article

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  100. Synthesis, crystal structure, DNA/protein interactions and cytotoxicity studies of tridentate ligand based Cu(II) complexes with various amine co-ligands

    Journal of Molecular Structure1970journal article

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