Skip to content
GraphTheory.in

Mukesh C. Sharma

School of Pharmacy,Devi Ahilya VishwavidyalayaIN
ORCID0000-0003-0222-5273
Claim this profile
h-index
24

via OpenAlex

Citations
2,630

via OpenAlex

Publications
53

About

Mukesh C. Sharma is an academic researcher at the School of Pharmacy, Devi Ahilya Vishwavidyalaya. He has authored 53 publications spanning from 2006 to 2015. Sharma's research focus lies in the application of molecular modeling and QSAR approaches to discover new biologically active compounds. His work covers a range of therapeutic areas, including antihypertensive agents, antibacterial agents, anti-malarial activity, and potent inhibitors.

Research areas

  • Chemistry
  • Medicine
  • Biology
  • Stereochemistry
  • Organic chemistry

Publications (53)

Sorted by most cited.

  1. 3D QSAR kNN-MFA studies on 6-substituted benzimidazoles derivatives as Nonpeptide Angiotensin II Receptor Antagonists: A rational approach to antihypertensive agents

    2011

    View DOI
    52 cites

  2. Synthesis and QSAR studies on 5-[2-(2-methylprop1-enyl)-1H benzimidazol-1yl]-4,6-diphenyl-pyrimidin-2-(5H)-thione derivatives as antibacterial agents

    2006

    View DOI
    48 cites

  3. Insight into the structural requirement of substituted quinazolinone biphenyl acylsulfonamides derivatives as Angiotensin II AT1 receptor antagonist: 2D and 3D QSAR approach

    2011

    View DOI
    31 cites

  4. Pharmacophore and QSAR modeling of some structurally diverse azaaurones derivatives as anti-malarial activity

    2013

    View DOI
    25 cites

  5. Comparative QSAR and pharmacophore modeling of substituted 2-[2′-(dimethylamino) ethyl]-1, 2-dihydro-3H-dibenz[de,h]isoquinoline-1,3-diones derivatives as anti-tumor activity

    2013

    View DOI
    20 cites

  6. Molecular modeling and pharmacophore approach for structural requirements of some 2-substituted-1-naphthols derivatives as potent 5-lipoxygenase inhibitors

    2013

    View DOI
    15 cites

  7. Molecular modelling studies for the discovery of new substituted pyridines derivatives with angiotensin II AT1 receptor antagonists

    2014

    View DOI
    9 cites

  8. Structural requirements of<i>N</i>-aryl-oxazolidinone-5-carboxamide derivatives for anti-HIV protease activity using molecular modelling techniques

    2013

    View DOI
    8 cites

  9. Discovery of Potent Antihypertensive Ligands Substituted Imidazolyl Biphenyl Sulfonylureas Analogs as Angiotensin II $$\hbox {AT}_{1}$$ AT 1 Receptor Antagonists by Molecular Modelling Studies

    2015

    View DOI
    4 cites

  10. Discovery of potent antihypertensive ligands substituted imidazolyl biphenyl sulfonylureas analogs as angiotensin II AT1 receptor antagonists by molecular modelling studies

    2014

    View DOI
    2 cites

  11. Mechanistic and AI-assisted evaluation of paclitaxel-loaded HSPC liposomes for targeted breast cancer therapy

    Naunyn-Schmiedeberg's Archives of Pharmacology2026journal article

    View DOI
    0 cites

  12. Gene Therapy as a Novel Strategy for Alzheimer’s Disease: Efficacy and Long-Term Implications

    Current Gene Therapy2026journal article

    View DOI
    0 cites

  13. Harnessing Artificial Intelligence in Drug Discovery and Alzheimer's Diagnosis: Tools, Applications, and Explainable Models for Next-Generation Therapeutics

    Current Drug Discovery Technologies2026journal article

    View DOI
    0 cites

  14. The RhoA/ROCK pathway in vascular dysfunction and inflammation: Mechanisms and therapeutic targeting

    European Journal of Inflammation2026journal article

    View DOI
    0 cites

  15. Emerging Roles of Small-molecule Derivatives in Modulating Neurodegenerative Pathways: From Molecular Targets to Therapeutic Applications

    Mini-Reviews in Medicinal Chemistry2026journal article

    View DOI
    0 cites

  16. Neuroprotective effects of Gynostemma pentaphyllum (Jiaogulan): Mechanisms, active compounds, and therapeutic potential

    Pharmacological Research - Modern Chinese Medicine2026journal article

    View DOI
    0 cites

  17. Comorbidity of Depression and Diabetes: A Literature Review on Systemic Flaws in Healthcare and the Benefits of Collaborative Diagnosis and Treatment in Primary Care Settings

    Current Diabetes Reviews2025journal article

    View DOI
    0 cites

  18. Research on Alzheimer's Disease (AD) Involving the Use of In vivo and In vitro Models and Mechanisms

    Central Nervous System Agents in Medicinal Chemistry2025journal article

    View DOI
    0 cites

  19. A Delve into the Chemical Diversity, Pharmacological Targets, and Biological Mechanisms of Ichnocarpous frutescens Linn R. Br.: A Review on the Current Status of Knowledge

    Current Organic Chemistry2025journal article

    View DOI
    0 cites

  20. Unveiling the therapeutic potential of traditional Chinese medicine Rhizome Coptidis: A comprehensive review

    Pharmacological Research - Modern Chinese Medicine2024journal article

    View DOI
    0 cites

  21. AI in Clinical Trials and Drug Development: Challenges and Potential Advancements

    Current Drug Discovery Technologies2024journal article

    View DOI
    0 cites

  22. Biomarkers and Novel Therapies of Diabetic Neuropathy: An Updated Review

    Current Pharmaceutical Biotechnology2024journal article

    View DOI
    0 cites

  23. Detailed review on phytosomal formulation attenuating new pharmacological therapies

    Advances in Traditional Medicine2024journal article

    View DOI
    0 cites

  24. Quality-by-Design (QbD) Assisted Synthesis of Nanoparticle for Efficient Loading, Stabilization, and Intracellular Delivery of Bioactive for the Treatment of Arthritis

    Indian Journal of Microbiology2024journal article

    View DOI
    0 cites

  25. Rapid, Simple and Low-Cost Reverse-Phase High-Performance Liquid Chromatography Tool for Estimation of Methotrexate: Testing Application in Standard Laboratory Bulk, Marketed Dosage Form, and Release kinetics in Nanoformulation

    Indian Journal of Pharmaceutical Education and Research2024journal article

    View DOI
    0 cites

  26. A Comprehensive Review on the Significance of Cysteine in Various Metabolic Disorders; Particularly CVD, Diabetes, Renal Dysfunction, and Ischemic Stroke

    Current Protein &amp; Peptide Science2024journal article

    View DOI
    0 cites

  27. Polymer mediated light responsive therapeutics delivery system to treat cancer

    European Polymer Journal2024journal article

    View DOI
    0 cites

  28. Metallic nanoparticles in cancer: Types, green synthesis, applications, tumor microenvironment and toxicity considerations

    Journal of Drug Delivery Science and Technology2024journal article

    View DOI
    0 cites

  29. Photoresponsive ‘Chemo-Free’ Phytotherapy: Formulation Development For the Treatment of Triple-Negative Breast Cancer

    Nanomedicine2024journal article

    View DOI
    0 cites

  30. Anticancer Properties of Some Selected Plant Phenolic Compounds: Future Leads for Therapeutic Development

    Journal of Herbal Medicine2023journal article

    View DOI
    0 cites

  31. 32 Factorial Design of O/W Nanoemulsions of Cholecalciferol Using Box–Behnken Model for Plaque Psoriasis

    Indian Journal of Pharmaceutical Education and Research2023journal article

    View DOI
    0 cites

  32. Recent Advances in Polymer-Based Nanomaterials for Non-Invasive Photothermal Therapy of Arthritis

    Pharmaceutics2023journal article

    View DOI
    0 cites

  33. Designing of novel nanoemulsions of retinol using box Behnken design for psoriasis

    Materials Today: Proceedings2022journal article

    View DOI
    0 cites

  34. Laser empowered ‘chemo-free’ phytotherapy: Newer approach in anticancer therapeutics delivery

    Journal of Drug Delivery Science and Technology2022journal article

    View DOI
    0 cites

  35. RP-HPLC-PDAAnalyses of Tapentadol: Application of Experimental Design

    Analytical Chemistry Letters2016journal article

    View DOI
    0 cites

  36. Graphene-based hybrid nanoparticle of doxorubicin for cancer chemotherapy

    International Journal of Nanomedicine1970journal article

    View DOI
    0 cites

  37. Development and validation of new analytical methods for simultaneous estimation of Drotaverine hydrochloride in combination with Omeprazole in a pharmaceutical dosage form

    Arabian Journal of Chemistry1970journal article

    View DOI
    0 cites

  38. Simultaneous determination of Nitazoxanide and Ofloxacin in pharmaceutical preparations using UV-spectrophotometric and high performance thin layer chromatography methods

    Arabian Journal of Chemistry1970journal article

    View DOI
    0 cites

  39. Molecular modeling studies of 3-acyl-2-phenylamino-1,4-dihydroquinolin-4-one derivatives as phosphatase SerB653 inhibitors

    Medicinal Chemistry Research1970journal article

    View DOI
    0 cites

  40. A Structure-Activity Relationship Study of Imidazole-5-Carboxylic Acid Derivatives as Angiotensin II Receptor Antagonists Combining 2D and 3D QSAR Methods

    Interdisciplinary Sciences: Computational Life Sciences1970journal article

    View DOI
    0 cites

  41. Development and validation of Spectrophotometric method and TLC Densitometric Determination of Irinotecan HCl in pharmaceutical dosage forms

    Arabian Journal of Chemistry1970journal article

    View DOI
    0 cites

  42. Identification of 3-Nitro-2,4,6-trihydroxybenzamide Derivatives as Photosynthetic Electron Transport Inhibitors by QSAR and Pharmacophore Studies

    Interdisciplinary Sciences: Computational Life Sciences1970journal article

    View DOI
    0 cites

  43. Investigation on Quantitative Structure Activity Relationships of a Series of Inducible Nitric Oxide

    Interdisciplinary Sciences: Computational Life Sciences1970journal article

    View DOI
    0 cites

  44. Structural features of substituted triazole-linked chalcone derivatives as antimalarial activities against D10 strains of Plasmodium falciparum: A QSAR approach

    Journal of Central South University1970journal article

    View DOI
    0 cites

  45. An approach to design potent anti-Alzheimer’s agents by 3D-QSAR studies on fused 5,6-bicyclic heterocycles as γ-secretase modulators using kNN–MFA methodology

    Arabian Journal of Chemistry1970journal article

    View DOI
    0 cites

  46. From Blended to Inclusive Learning: Accessibility, Profiles, Openness, and Higher Education

    Journal of Universal Computer Science1970journal article

    View DOI
    0 cites

  47. Structural insights for substituted acyl sulfonamides and acyl sulfamides derivatives of imidazole as angiotensin II receptor antagonists using molecular modeling approach

    Journal of the Taiwan Institute of Chemical Engineers1970journal article

    View DOI
    0 cites

  48. Synthesis, docking studies and antioxidant activity of some chalcone and aurone derivatives

    Medicinal Chemistry Research1970journal article

    View DOI
    0 cites

  49. QSAR studies of some substituted imidazolinones angiotensin II receptor antagonists using Partial Least Squares Regression (PLSR) method based feature selection

    Journal of Saudi Chemical Society1970journal article

    View DOI
    0 cites

  50. Molecular Modeling Studies of Substituted 2,4,5-Trisubstituted Triazolinones Aryl and Nonaryl Derivatives as Angiotensin II AT <sub> <b>1</b> </sub> Receptor Antagonists

    Research & Reviews: Journal of Chemistry1970journal article

    View DOI
    0 cites

  51. QSAR STUDY OF SOME SUBSTITUTED 4-QUINOLINYL AND 9-ACRIDINYL HYDRAZONES AS ANTIMALARIAL AGENTS

    Acta Poloniae Pharmaceutica1970journal article

    0 cites

  52. QSAR studies on imidazopyridazine derivatives as PfPK7 inhibitors

    Molecular Simulation1970journal article

    View DOI
    0 cites

  53. 2D-QSAR STUDIES OF SOME 1, 3, 4-THIDIAZOLE-2YL AZETIDINE 2-ONE AS ANTIMICROBIAL ACTIVITY

    Digest Journal of Nanomaterials and Biostructures1970journal article

    0 cites