- h-index
- 29
- Citations
- 3,112
- Publications
- 189
via OpenAlex
via OpenAlex
About
N. S. Hari Narayana Moorthy is a researcher at Indira Gandhi National Tribal University. With a research focus on computational chemistry and pharmacoinformatics, Moorthy has published 89 papers over the span of 1970 to 2020, covering topics such as QSAR modeling, machine learning, and structure-activity relationships.
Research areas
- Chemistry
- Stereochemistry
- Biochemistry
- Organic chemistry
- Biology
Publications (189)
Sorted by most cited.
- 315 cites
- 278 cites
- 245 cites
Protein-ligand docking in the new millennium - A retrospective of 10 years in the field
1970journal article
View DOI - 182 cites
Current knowledge on the distribution of arsenic in groundwater in five states of India
1970journal article
View DOI - 96 cites
- 71 cites
Recent Advances in Protein Tyrosine Phosphatase 1B Targeted Drug Discovery for Type II Diabetes and Obesity
2017
View DOI - 69 cites
- 66 cites
The Rise and Fall of Chloroquine/Hydroxychloroquine as Compassionate Therapy of COVID-19
2021
View DOI - 59 cites
Aryl- and Heteroaryl-Thiosemicarbazone Derivatives and Their Metal Complexes: A Pharmacological Template
2013
View DOI - 54 cites
6H-Indolo[2,3-b]Quinoxalines: DNA and Protein Interacting Scaffold for Pharmacological Activities
2013
View DOI - 45 cites
Synthesis of Some Coumarinyl Chalcones and their Antiproliferative Activity Against Breast Cancer Cell Lines
2011
View DOI - 42 cites
Farnesyltransferase inhibitors: A comprehensive review based on quantitative structural analysis
Current Medicinal Chemistry1970journal article
View DOI - 41 cites
Recent Patents on Anti-Cancer Drug Discovery1970journal article
View DOI - 41 cites
Chemical and Pharmaceutical Bulletin1970journal article
View DOI - 39 cites
Design, synthesis and biological evaluation of some novel 3-cinnamoyl-4-hydroxy-2H-chromen-2-ones as antimalarial agents
Medicinal Chemistry Research1970journal article
View DOI - 38 cites
Microwave-Assisted Functionalization of Multi-Walled Carbon Nanotubes for Biosensor and Drug Delivery Applications
2023
View DOI - 35 cites
Recent Advances in the Development of Fatty Acid Synthase Inhibitors as Anticancer Agents
2020
View DOI - 34 cites
- 34 cites
QSAR analysis of 2-benzoxazolyl hydrazone derivatives for anticancer activity and its possible target prediction
Medicinal Chemistry Research1970journal article
View DOI - 34 cites
Mini-Reviews in Medicinal Chemistry1970journal article
View DOI - 32 cites
Development of ribonucleotide reductase inhibitor: A review on structure activity relationships
1970journal article
View DOI - 31 cites
Repaglinide-laden hydrogel particles of xanthan gum derivatives for the management of diabetes
2022
View DOI - 30 cites
- 29 cites
Lysinated Multiwalled Carbon Nanotubes with Carbohydrate Ligands as an Effective Nanocarrier for Targeted Doxorubicin Delivery to Breast Cancer Cells
2022
View DOI - 29 cites
Human Ether-a-Go-Go-Related Gene Channel Blockers and its Structural Analysis for Drug Design
2013
View DOI - 28 cites
- 28 cites
lH-Pyrazolo[3,4-b]quinolin-3-amine derivatives inhibit growth of colon cancer cells via apoptosis and sub G1 cell cycle arrest
2018
View DOI - 28 cites
Comparative studies on conventional and microwave assisted synthesis of benzimidazole and their 2-substituted derivative with the effect of salt form of reactant
Chemical & Pharmaceutical Bulletin1970journal article
View DOI - 27 cites
Design and discovery of silybin analogues as antiproliferative compounds using a ring disjunctive – Based, natural product lead optimization approach
2017
View DOI - 27 cites
Iodine-catalyzed, one-pot, solid-phase synthesis of benzothiazole derivatives
1970journal article
View DOI - 26 cites
3D QSAR of aminophenyl benzamide derivatives as histone deacetylase inhibitors
1970journal article
View DOI - 24 cites
Design, synthesis and biological evaluation of some tetrazole acetamide derivatives as novel non-carboxylic PTP1B inhibitors
2019
View DOI - 24 cites
- 24 cites
QSAR modelling of HIV-1 reverse transcriptase inhibition by benzoxazinones using a combination of P_VSA and pharmacophore feature descriptors
Bioorganic & Medicinal Chemistry Letters1970journal article
View DOI - 24 cites
Design, synthesis, cytotoxic evaluation, and QSAR study of some 6H-indolo[2,3-b]quinoxaline derivatives
Journal of Enzyme Inhibition and Medicinal Chemistry1970journal article
View DOI - 22 cites
- 21 cites
Structural feature study of benzofuran derivatives as farnesyltransferase inhibitors
Journal of Enzyme Inhibition and Medicinal Chemistry1970journal article
View DOI - 18 cites
Synthesis and biological evaluation of some N-(3-(1H-tetrazol-5-yl) phenyl)acetamide derivatives as novel non-carboxylic PTP1B inhibitors designed through bioisosteric modulation
2018
View DOI - 18 cites
Classification study of solvation free energies of organic molecules using machine learning techniques
2014
View DOI - 17 cites
Topological, hydrophobicity, and other descriptors on α-glucosidase inhibition: a QSAR study on xanthone derivatives
2011
View DOI - 17 cites
Prediction of the relationship between the structural features of andrographolide derivatives and alpha-glucosidase inhibitory activity: A quantitative structure-activity relationship (QSAR) Study
Journal of Enzyme Inhibition and Medicinal Chemistry1970journal article
View DOI - 16 cites
Synthesis, antifungal evaluation and in silico study of novel Schiff bases derived from 4-amino-5(3,5-dimethoxy-phenyl)-4H-1,2,4-triazol-3-thiol
2014
View DOI - 16 cites
QSAR Analysis of Isosteviol Derivatives as α-Glucosidase Inhibitors with Element Count and Other Descriptors
2010
View DOI - 16 cites
HERG binding feature analysis of structurally diverse compounds by QSAR and fragmental analysis
1970journal article
View DOI - 16 cites
A new approach for PEGylation of dendrimers
Bioorganic & Medicinal Chemistry Letters1970journal article
View DOI - 15 cites
- 15 cites
- 15 cites
In Silico-Based Structural Analysis of Arylthiophene Derivatives for FTase Inhibitory Activity, hERG, and Other Toxic Effects
Journal of Biomolecular Screening1970journal article
View DOI - 15 cites
QSAR analysis of some 5-amino-2-mercapto-1,3,4-thiadiazole based inhibitors of matrix metalloproteinases and bacterial collagenase
Bioorganic & Medicinal Chemistry Letters1970journal article
View DOI - 14 cites
- 14 cites
- 14 cites
Comparative Structural Analysis of a-Glucosidase Inhibitors on Difference Species: A Computational Study
Archiv Der Pharmazie1970journal article
View DOI - 14 cites
COMPARATIVE STUDY OF FORCED DEGRADATION BEHAVIOR OF PRASUGREL BY UPLC AND HPLC AND THE DEVELOPMENT OF VALIDATED STABILITY INDICATING ASSAY METHOD
Journal of Liquid Chromatography & Related Technologies1970journal article
View DOI - 12 cites
- 11 cites
Antiproliferative Efficacy of N-(3-chloro-4-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine, DW-8, in Colon Cancer Cells Is Mediated by Intrinsic Apoptosis
2021
View DOI - 11 cites
Medicinal Chemistry Research1970journal article
View DOI - 10 cites
- 10 cites
A Novel Dialkylamino-Functionalized Chalcone, DML6, Inhibits Cervical Cancer Cell Proliferation, In Vitro, via Induction of Oxidative Stress, Intrinsic Apoptosis and Mitotic Catastrophe
2021
View DOI - 10 cites
Multi-algorithm based machine learning and structural pattern studies for hERG ion channel blockers mediated cardiotoxicity prediction
2020
View DOI - 10 cites
Molecular dynamic simulations and structure-based pharmacophore development for farnesyltransferase inhibitors discovery
2016
View DOI - 10 cites
A new simple and rapid validated RP-HPLC method for determination of ziprasidone in ziprasidone capsules
2012
View DOI - 10 cites
Analysis of the α-Glucosidase Inhibitory Activity of Chromenone Derivatives Based on their Molecular Features: A Computational Study
2011
View DOI - 10 cites
Quantitative Structure-Activity Relationships of Selective Antagonists of Glucagon Receptor Using QuaSAR Descriptors
2006
View DOI - 9 cites
Design, synthesis, and anticancer activity of some novel 1H-benzo[d]imidazole-5-carboxamide derivatives as fatty acid synthase inhibitors
2023
View DOI - 9 cites
Synthesis and Anti-microbial Evaluation of Some 3, 4-Dihydro Pyrimidine-2-one Derivatives
2008
View DOI - 8 cites
Classification analysis of fatty acid synthase inhibitors using multialgorithms on topological descriptors and structural fingerprints
2022
View DOI - 7 cites
Use of lysinated multiwalled carbon nanotubes with carbohydrate ligands as a doxorubicin nanocarrier: A molecular dynamics analysis
2023
View DOI - 7 cites
Novel 3-((2-chloroquinolin-3-yl)methylene)indolin-2-one derivatives produce anticancer efficacy in ovarian cancer in vitro
2019
View DOI - 7 cites
Development and validation of a RP-HPLC method for determination of citicoline monosodium in human plasma
2011
- 7 cites
QSAR studies of cytotoxic acridine 5,7-diones : A comparative study using P-VSA descriptors and topological descriptors
2007
- 7 cites
QSAR Modeling of Some 2-methoxy Acridones: Cytotoxic Agents in Multi Drug Resistant Cells
2006
View DOI - 7 cites
Structural analysis of structurally diverse alpha-glucosidase inhibitors for active site feature analysis
Journal of Enzyme Inhibition and Medicinal Chemistry1970journal article
View DOI - 6 cites
- 6 cites
Dual mechanism of HIV-1 integrase and RNase H inhibition by diketo derivatives – a computational study
2014
View DOI - 6 cites
- 6 cites
Combined ligand and structure based binding mode analysis of oxidosqualene cyclase inhibitors
RSC Advances1970journal article
View DOI - 6 cites
Synthesis, in silico metabolic and toxicity prediction of some novel imidazolinones derivatives as potent anticonvulsant agents
Journal of Enzyme Inhibition and Medicinal Chemistry1970journal article
View DOI - 5 cites
- 5 cites
Design, Synthesis and Biological Evaluation of 3-(2-(benzo[d]thiazol-2- ylthio)acetamido)benzoic Acid Derivatives as Inhibitors of Protein Tyrosine Phosphatase 1B
2020
View DOI - 5 cites
QSAR studies and molecular shape analysis of azonafide derivatives as topoisomerase II inhibitors
2003
- 4 cites
Novel isatin-chalcone molecular hybrids endowed with potent antistaphylococcal properties: In vitro and mechanistic insights
2026
View DOI - 4 cites
Metabolite profiling, antimalarial potentials of Schleichera oleosa using LC-MS and GC-MS: in vitro, molecular docking and molecular dynamics
2025
View DOI - 4 cites
In silico-guided discovery and in vitro validation of novel sugar-tethered lysinated carbon nanotubes for targeted drug delivery of doxorubicin
2024
View DOI - 4 cites
Ascendancy of <scp>pH</scp>‐irresponsive Moi gum in the design of modified xanthan gum semi‐interpenetrating network hydrogels for monitoring diabetes
2022
View DOI - 4 cites
Structure based virtual screening of natural product molecules as glycosidase inhibitors
2021
View DOI - 4 cites
- 4 cites
QSAR and Pharmacophore Analysis of a Series of Piperidinyl Urea Derivatives as hERG Blockers and H3 Antagonists
2013
View DOI - 4 cites
Synthesis, Biological Evaluation and in silico Metabolic and Toxicity Prediction of Some Flavanone Derivatives.
2007
View DOI - 4 cites
- 4 cites
- 4 cites
Modeling VEGFR kinase inhibition of aminopyrazolopyridine urea derivatives using topological and physicochemical descriptors: a quantitative structure activity analysis study
Medicinal Chemistry Research1970journal article
View DOI - 3 cites
Design, synthesis, and pharmacological evaluation of heteroaryl thiol-linked kojic acid derivatives as a novel class of acetylcholinesterase inhibitors for Alzheimer’s disease therapy
2025
View DOI - 3 cites
- 3 cites
- 3 cites
- 3 cites
Simultaneous spectrophotometric methods for the estimation of nimesulide and tizanidine in a tablet dosage form
2005
- 3 cites
In silico based structural analysis of some piperidine analogs as farnesyltransferase inhibitors
1970journal article
View DOI - 2 cites
In Silico Based Structural and Fingerprint Analysis of Structurally Diverse AT1 inhibitors
2020
View DOI - 2 cites
Quantitative Structure Activity Relationship Analysis of Some Diarylsulphonylurea Derivatives as Tubulin Binding Agents
2007
View DOI - 2 cites
QSAR study on hetaryl imidazoles: A novel dual inhibitor of VEGF receptors I and II
1970journal article
View DOI - 1 cites
Targeted Delivery of Doxorubicin to Breast Cancer Cells by Multiwalled Carbon Nanotubes Functionalized with Lysine via 1,3-Dipolar Cycloaddition and Conjugation with Sugar Moieties
2022
View DOI - 1 cites
Targeting Angiotensin-converting Enzyme 2 (ACE2) for the Discovery of Anticoronaviral Drugs
2022
View DOI - 1 cites
- 1 cites
Binding mode of conformations and structure-based pharmacophore development for farnesyltransferase inhibitors
2016
View DOI - 1 cites
Human Ether-a-Go-Go-Related Gene Channel Blockers and its Structural Analysis for Drug Design
2012
View DOI - 1 cites
Determination of salmeterol xinafoate and its degradation products according to ICH guidelines with use of UPLC technique
2011
- 1 cites
RP-HPLC method for simultaneous estimation of amlodipine and valsartan in tablet formulation and validation as per ICH guidelines
2011
- 1 cites
QSAR Analysis of HIV-1 Reverse Transcriptase Inhibitory 5-Alkyl-2- [(Aryl and Alkyloxylcarbonylmethyl)Thio]-6- (1-Napthylmethyl) Pyrimidin-4 (3H)-Ones*
2010
View DOI - 1 cites
- 1 cites
Quantitative structure activity analysis of 2-alkoxydihydrocinnamates as PPAR alpha/gamma dual agonist
Medicinal Chemistry1970journal article
View DOI - 0 cites
Investigation of plant-derived compounds as potent inhibitors of casein kinase-1 alpha through computational analysis and molecular dynamic simulations
2026
View DOI - 0 cites
Synthesis, Biological evaluation, and computational study of 2-((2-oxo-2-(arylamino)ethyl)thio)-1H-benzo[d]imidazole-5-carboxylic acids as PTP1B inhibitors for the treatment of type 2 diabetes
2026
View DOI - 0 cites
Identification and Mechanistic Profiling of Indolin‐2‐One Derivatives That Induce ROS‐Driven Intrinsic Apoptosis in Prostate and Colorectal Cancer Cells
2025
View DOI - 0 cites
Design, synthesis and biological evaluation of 2-phenylquinoxaline carbonyl piperazine derivatives as novel FASN inhibitors with anticancer activity
2025
View DOI - 0 cites
- 0 cites
Machine learning-based analysis on retention time of pesticides for eco-friendly and cost-effective analytical method development
2025
View DOI - 0 cites
- 0 cites
- 0 cites
Design, Synthesis and Biological Evaluation of Novel 1H-benzo[d]imidazole Derivatives as Fatty Acid Synthase (FASN) Inhibitors for Cancer Treatment
2022
View DOI - 0 cites
Molecular Dynamic Simulations-Based Conformational Analysis and Binding Study of CP-225917 on Farnesyl Transferase Enzyme
2022
View DOI - 0 cites
- 0 cites
Synthesis, biological evaluation and molecular docking studies of 4-arylidene-2-phenyloxazol-5(4H)-one derivatives as inhibitors of dual-specificity tyrosine phosphorylation-regulated kinases and Cdc2-like kinases
2021
View DOI - 0 cites
- 0 cites
Plant derived active compounds as potential anti SARS-CoV-2 agents: an <i>in-silico</i> study
2021
View DOI - 0 cites
Binding Mode Prediction and Identification of New Lead Compounds from Natural Products as 3-OST Enzyme Inhibitors
2020
View DOI - 0 cites
Natural Products in Clinical Trials
2018
- 0 cites
- 0 cites
Synthesis, characterization and biological evaluation of N-(5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-yl)-4-nitrobenzamide derivatives
2015
- 0 cites
Anticancer activities of chalcones: A review on patent perspective
Recent Patents in Anticancer Drug Discovery2014journal article
- 0 cites
Dual Mechanism of HIV-1 Integrase and RNase H Inhibition by Diketo Derivatives: A computational study.
RSC Advances2014journal article
- 0 cites
Fused aryl-phenazines: Scaffold for the development of bioactive molecules.
Current Drug Targets2014journal article
- 0 cites
Synthesis, Antifungal Evaluation and In silico Study of Novel Schiff Bases Derived from 4-amino-5(3,5-dimethoxy-phenyl)-4H-1,2,4-triazol-3-thiol.
Arabian Journal of Chemistry2014journal article
View DOI - 0 cites
A new simple and rapid validated RP-UPLC method for determination of ziprasidone in ziprasidone capsules.
Journal of Saudi Chemical Society2014journal article
View DOI - 0 cites
Farnesyltransferase Inhibitors: A Comprehensive Review Based on Quantitative Structural Analysis
Current Medicinal Chemistry2013journal article
- 0 cites
Iconography : Synthesis and evaluation of some amino acid conjugates of suprofen
2013
- 0 cites
Structurally modified celecoxib analogues for selective COX-2 inhibition: a classical hansch QSAR approach
2012
- 0 cites
Study of forced degradation behaviour of eprosartan mesylate and development of validated stability indicating assay method by UPLC
2011
- 0 cites
RP-HPLC method for estimation and stability study of drotaverine HCl as per ICH guidelines
2011
- 0 cites
ChemInform Abstract: Iodine‐Catalyzed, One‐Pot, Solid‐Phase Synthesis of Benzothiazole Derivatives.
2008
View DOI - 0 cites
QSAR Studies of 6‐Amino Uracil Base Analogues: A Thymidine Phosphorylase Inhibitor in Cancer Therapy
2007
View DOI - 0 cites
6H-Indolo[2,3-b]Quinoxalines: DNA and Protein Interacting Scaffold for Pharmacological Activities
Mini-Reviews in Medicinal Chemistry1970journal article
- 0 cites
Human ether-a-go-go-related gene channel blockers and its structural analysis for drug design
1970journal article
- 0 cites
QSAR analysis and pharmacophore mapping of catecholic flavonoids for telomerase inhibitory activity
1970journal article
- 0 cites
Determination of Salmeterol Xinafoate and its Degradation Products According to ICH Guidelines with use of UPLC Technique
Latin American Journal of Pharmacy1970journal article
- 0 cites
QSAR Analysis of Isosteviol Derivatives as alpha-Glucosidase Inhibitors with Element Count and Other Descriptors
Letters in Drug Design & Discovery1970journal article
- 0 cites
RP-HPLC method for estimation and stability study of drotaverine HCl as per ICH guidelines
1970journal article
- 0 cites
Topological, hydrophobicity, and other descriptors on alpha-glucosidase inhibition: a QSAR study on xanthone derivatives
Journal of Enzyme Inhibition and Medicinal Chemistry1970journal article
View DOI - 0 cites
Design, synthesis and characterization of novel 1,3,4-oxadiazole dimers from benzoic acids
1970journal article
- 0 cites
Synthesis and characterization of some mannich bases as potential antimicrobial agents
1970journal article
- 0 cites
QSAR studies of 6-amino uracil base analogues: A thymidine phosphorylase inhibitor in cancer therapy
1970journal article
- 0 cites
AIDS: A review of targets and approaches for treatment
1970journal article
- 0 cites
QSAR analysis of 5,6-dihydro-4-hydroxy-2-pyrone analogues: HIV-1 protease inhibitor
Asian Journal of Chemistry1970journal article
- 0 cites
QSAR studies of benzylidene-9(10H) anthracenone derivatives: Tubulin inhibitor in cancer therapy
1970journal article
- 0 cites
QSAR study of anticancer agents: 1,8-Naphthyridine derivatives
Asian Journal of Chemistry1970journal article
- 0 cites
DNA fingerprinting: A prophecy fulfilled
Pharma Times1970journal article
- 0 cites
Indian Journal of Pharmaceutical Sciences1970journal article
- 0 cites
QSAR modeling of some 2-methoxy acridones: Cytotoxic in multi drug resistant cells
International Journal of Cancer Research1970journal article
- 0 cites
QSAR studies of 2-aroylindole derivatives: Tubulin inhibitors in cancer therapy
Asian Journal of Chemistry1970journal article
- 0 cites
QSAR studies of anti-malarial agents: 2,4-Diamino pyrimidine derivatives
Asian Journal of Chemistry1970journal article
- 0 cites
Quantitative structure - Activity relationships of selective antagonists of glucagon receptor using QuaSAR descriptors
Chemical & Pharmaceutical Bulletin1970journal article
- 0 cites
Indian Journal of Pharmaceutical Sciences1970journal article
- 0 cites
QSAR studies and molecular shape analysis of azonafide derivatives as topoisomerase II inhibitors
Indian Journal of Pharmaceutical Sciences1970journal article