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N. S. Hari Narayana Moorthy

Indira Gandhi National Tribal UniversityIN
ORCID0000-0003-2300-4074
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28

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Citations
3,087

via OpenAlex

Publications
89

About

N. S. Hari Narayana Moorthy is a researcher at Indira Gandhi National Tribal University. With a research focus on computational chemistry and pharmacoinformatics, Moorthy has published 89 papers over the span of 1970 to 2020, covering topics such as QSAR modeling, machine learning, and structure-activity relationships.

Research areas

  • Chemistry
  • Stereochemistry
  • Biochemistry
  • Organic chemistry
  • Biology

Publications (89)

Sorted by most cited.

  1. Classification of carcinogenic and mutagenic properties using machine learning method

    2017

    View DOI
    30 cites

  2. QSAR modelling of HIV-1 reverse transcriptase inhibition by benzoxazinones using a combination of P_VSA and pharmacophore feature descriptors

    Bioorganic & Medicinal Chemistry Letters1970journal article

    View DOI
    24 cites

  3. QSAR analysis of some phthalimide analogues based inhibitors of HIV-1 integrase

    1970journal article

    15 cites

  4. Multi-algorithm based machine learning and structural pattern studies for hERG ion channel blockers mediated cardiotoxicity prediction

    2020

    View DOI
    10 cites

  5. Modeling VEGFR kinase inhibition of aminopyrazolopyridine urea derivatives using topological and physicochemical descriptors: a quantitative structure activity analysis study

    Medicinal Chemistry Research1970journal article

    View DOI
    4 cites

  6. QSAR study on hetaryl imidazoles: A novel dual inhibitor of VEGF receptors I and II

    1970journal article

    View DOI
    2 cites

  7. Anticancer activities of chalcones: A review on patent perspective

    Recent Patents in Anticancer Drug Discovery2014journal article

    0 cites

  8. Dual Mechanism of HIV-1 Integrase and RNase H Inhibition by Diketo Derivatives: A computational study.

    RSC Advances2014journal article

    0 cites

  9. Fused aryl-phenazines: Scaffold for the development of bioactive molecules.

    Current Drug Targets2014journal article

    0 cites

  10. Synthesis, Antifungal Evaluation and In silico Study of Novel Schiff Bases Derived from 4-amino-5(3,5-dimethoxy-phenyl)-4H-1,2,4-triazol-3-thiol.

    Arabian Journal of Chemistry2014journal article

    View DOI
    0 cites

  11. A new simple and rapid validated RP-UPLC method for determination of ziprasidone in ziprasidone capsules.

    Journal of Saudi Chemical Society2014journal article

    View DOI
    0 cites

  12. Farnesyltransferase Inhibitors: A Comprehensive Review Based on Quantitative Structural Analysis

    Current Medicinal Chemistry2013journal article

    0 cites

  13. Analysis of surface area features of structurally diverse molecules for Bcr/Abl kinase inhibitory activity and antiproliferative activity

    1970journal article

    View DOI
    0 cites

  14. Atom based 3D-QSAR study of 1,4-benzodiazepine-2-ones as potent anti-trypanosomal agents and its validation

    1970journal article

    View DOI
    0 cites

  15. Binding mode prediction and identification of new lead compounds from natural products as renin and angiotensin converting enzyme inhibitors

    1970journal article

    View DOI
    0 cites

  16. Human CDC2-like kinase 1 (CLK1): A novel target for Alzheimer's disease

    1970journal article

    View DOI
    0 cites

  17. Predictive QSAR models development and validation for human ether-a-go-go related gene (hERG) blockers using newer tools

    1970journal article

    View DOI
    0 cites

  18. Farnesyltransferase inhibitors: A comprehensive review based on quantitative structural analysis

    Current Medicinal Chemistry1970journal article

    View DOI
    0 cites

  19. 6H-Indolo[2,3-b]Quinoxalines: DNA and Protein Interacting Scaffold for Pharmacological Activities

    Mini-Reviews in Medicinal Chemistry1970journal article

    0 cites

  20. Aryl-and heteroaryl-thiosemicarbazone derivatives and their metal complexes: A pharmacological template

    Recent Patents on Anti-Cancer Drug Discovery1970journal article

    View DOI
    0 cites

  21. Combined ligand and structure based binding mode analysis of oxidosqualene cyclase inhibitors

    RSC Advances1970journal article

    View DOI
    0 cites

  22. Design, synthesis and biological evaluation of novel arylidine- malononitrile derivatives as non-carboxylic inhibitors of protein tyrosine phosphatase 1B

    Medicinal Chemistry Research1970journal article

    View DOI
    0 cites

  23. Design, synthesis and molecular modelling studies of novel 3-acetamido-4-methyl benzoic acid derivatives as inhibitors of protein tyrosine phosphatase 1B

    1970journal article

    View DOI
    0 cites

  24. Development of ribonucleotide reductase inhibitor: A review on structure activity relationships

    1970journal article

    View DOI
    0 cites

  25. Human ether-a-go-go-related gene channel blockers and its structural analysis for drug design

    1970journal article

    0 cites

  26. Protein-ligand docking in the new millennium - A retrospective of 10 years in the field

    1970journal article

    View DOI
    0 cites

  27. QSAR analysis and pharmacophore mapping of catecholic flavonoids for telomerase inhibitory activity

    1970journal article

    0 cites

  28. QSAR and pharmacophore analysis of a series of piperidinyl urea derivatives as hERG blockers and H3 antagonists

    1970journal article

    0 cites

  29. Analysis of van der Waals surface area properties for human ether-a-go-go-related gene blocking activity: Computational study on structurally diverse compounds

    1970journal article

    View DOI
    0 cites

  30. Comparative Structural Analysis of a-Glucosidase Inhibitors on Difference Species: A Computational Study

    Archiv Der Pharmazie1970journal article

    View DOI
    0 cites

  31. Design, synthesis and biological evaluation of some novel 3-cinnamoyl-4-hydroxy-2H-chromen-2-ones as antimalarial agents

    Medicinal Chemistry Research1970journal article

    View DOI
    0 cites

  32. In silico based structural analysis of some piperidine analogs as farnesyltransferase inhibitors

    1970journal article

    View DOI
    0 cites

  33. QSAR analysis of 2-benzoxazolyl hydrazone derivatives for anticancer activity and its possible target prediction

    Medicinal Chemistry Research1970journal article

    View DOI
    0 cites

  34. QSAR and pharmacophore analysis of thiosemicarbazone derivatives as ribonucleotide reductase inhibitors

    1970journal article

    View DOI
    0 cites

  35. Structural analysis of 2-piperidin-4-yl-actamide derivatives for hERG blocking and MCH R1 antagonistic activities

    1970journal article

    View DOI
    0 cites

  36. Structural analysis of structurally diverse alpha-glucosidase inhibitors for active site feature analysis

    Journal of Enzyme Inhibition and Medicinal Chemistry1970journal article

    View DOI
    0 cites

  37. Structurally modified celecoxib analogues for selective COX-2 inhibition: A classical hansch QSAR approach

    1970journal article

    0 cites

  38. Studies on α-glucosidase inhibitors development: Magic molecules for the treatment of carbohydrate mediated diseases

    1970journal article

    View DOI
    0 cites

  39. Synthesis, characterization, biological evaluation and docking of coumarin coupled thiazolidinedione derivatives and its bioisosteres as PPARγ agonists

    1970journal article

    View DOI
    0 cites

  40. Synthesis, in silico metabolic and toxicity prediction of some novel imidazolinones derivatives as potent anticonvulsant agents

    Journal of Enzyme Inhibition and Medicinal Chemistry1970journal article

    View DOI
    0 cites

  41. Virtual screening and QSAR study of some pyrrolidine derivatives as α-mannosidase inhibitors for binding feature analysis

    1970journal article

    View DOI
    0 cites

  42. A validated UPLC method used for the determination of trandolapril and its degradation products as per ICH guidelines

    1970journal article

    View DOI
    0 cites

  43. Analysis of the α-glucosidase inhibitory activity of chromenone derivatives based on their molecular features: A computational study

    1970journal article

    0 cites

  44. COMPARATIVE STUDY OF FORCED DEGRADATION BEHAVIOR OF PRASUGREL BY UPLC AND HPLC AND THE DEVELOPMENT OF VALIDATED STABILITY INDICATING ASSAY METHOD

    Journal of Liquid Chromatography & Related Technologies1970journal article

    View DOI
    0 cites

  45. Determination of Salmeterol Xinafoate and its Degradation Products According to ICH Guidelines with use of UPLC Technique

    Latin American Journal of Pharmacy1970journal article

    0 cites

  46. Development and validation of a RP-HPLC method for determination of citicoline monosodium in human plasma

    1970journal article

    0 cites

  47. HERG binding feature analysis of structurally diverse compounds by QSAR and fragmental analysis

    1970journal article

    View DOI
    0 cites

  48. In Silico-Based Structural Analysis of Arylthiophene Derivatives for FTase Inhibitory Activity, hERG, and Other Toxic Effects

    Journal of Biomolecular Screening1970journal article

    View DOI
    0 cites

  49. Prediction of the relationship between the structural features of andrographolide derivatives and alpha-glucosidase inhibitory activity: A quantitative structure-activity relationship (QSAR) Study

    Journal of Enzyme Inhibition and Medicinal Chemistry1970journal article

    View DOI
    0 cites

  50. QSAR Analysis of Isosteviol Derivatives as alpha-Glucosidase Inhibitors with Element Count and Other Descriptors

    Letters in Drug Design & Discovery1970journal article

    0 cites

  51. RP-HPLC method for estimation and stability study of drotaverine HCl as per ICH guidelines

    1970journal article

    0 cites

  52. RP-HPLC method for simultaneous estimation of amlodipine and valsartan in tablet formulation and validation as per ICH guidelines

    1970journal article

    0 cites

  53. Structural analysis of α-glucosidase inhibitors by validated QSAR models using topological and hydrophobicity based descriptors

    1970journal article

    View DOI
    0 cites

  54. Structural feature study of benzofuran derivatives as farnesyltransferase inhibitors

    Journal of Enzyme Inhibition and Medicinal Chemistry1970journal article

    View DOI
    0 cites

  55. Study of forced degradation behaviour of eprosartan mesylate and development of validated stability indicating assay method by UPLC

    1970journal article

    0 cites

  56. Synthesis of some coumarinyl chalcones and their antiproliferative activity against breast cancer cell lines

    1970journal article

    0 cites

  57. Topological, hydrophobicity, and other descriptors on alpha-glucosidase inhibition: a QSAR study on xanthone derivatives

    Journal of Enzyme Inhibition and Medicinal Chemistry1970journal article

    View DOI
    0 cites

  58. 3D QSAR of aminophenyl benzamide derivatives as histone deacetylase inhibitors

    1970journal article

    View DOI
    0 cites

  59. A new approach for PEGylation of dendrimers

    Bioorganic & Medicinal Chemistry Letters1970journal article

    View DOI
    0 cites

  60. Design, synthesis and characterization of novel 1,3,4-oxadiazole dimers from benzoic acids

    1970journal article

    0 cites

  61. Design, synthesis, cytotoxic evaluation, and QSAR study of some 6H-indolo[2,3-b]quinoxaline derivatives

    Journal of Enzyme Inhibition and Medicinal Chemistry1970journal article

    View DOI
    0 cites

  62. Synthesis and characterization of some mannich bases as potential antimicrobial agents

    1970journal article

    0 cites

  63. QSAR study of substituted 2-pyridinyl guanidines as selective urokinase-type plasminogen activator (uPA) inhibitors

    1970journal article

    View DOI
    0 cites

  64. QSAR study on N-(aryl)-4-(azolylethyl) thiazole-5-carboxamides: Novel potent inhibitors of VEGF receptors I and II

    1970journal article

    View DOI
    0 cites

  65. Quantitative structure activity relationship studies of piperazinyl phenylalanine derivatives as VLA-4/VCAM-1 inhibitors

    1970journal article

    View DOI
    0 cites

  66. Synthesis, characterization, biological evaluation and in silico study of some novel bis-piperidine derivatives

    1970journal article

    0 cites

  67. Synthesis, cytotoxic evaluation and in silico pharmacokinetic prediction of some benzo[a]phenazine-5-sulfonic acid derivatives

    1970journal article

    View DOI
    0 cites

  68. QSAR studies of 6-amino uracil base analogues: A thymidine phosphorylase inhibitor in cancer therapy

    1970journal article

    0 cites

  69. Quantitative structure activity analysis of 2-alkoxydihydrocinnamates as PPAR alpha/gamma dual agonist

    Medicinal Chemistry1970journal article

    View DOI
    0 cites

  70. Quantitative structure activity relationship analysis of some diarylsulphonylurea derivatives as tubulin binding agents

    1970journal article

    0 cites

  71. AIDS: A review of targets and approaches for treatment

    1970journal article

    0 cites

  72. Comparative studies on conventional and microwave assisted synthesis of benzimidazole and their 2-substituted derivative with the effect of salt form of reactant

    Chemical & Pharmaceutical Bulletin1970journal article

    View DOI
    0 cites

  73. Current knowledge on the distribution of arsenic in groundwater in five states of India

    1970journal article

    View DOI
    0 cites

  74. Iodine-catalyzed, one-pot, solid-phase synthesis of benzothiazole derivatives

    1970journal article

    View DOI
    0 cites

  75. QSAR analysis of 5,6-dihydro-4-hydroxy-2-pyrone analogues: HIV-1 protease inhibitor

    Asian Journal of Chemistry1970journal article

    0 cites

  76. QSAR studies of benzylidene-9(10H) anthracenone derivatives: Tubulin inhibitor in cancer therapy

    1970journal article

    0 cites

  77. QSAR studies of cytotoxic acridine 5,7-diones: A comparative study using P-VSA descriptors and topological descriptors

    1970journal article

    0 cites

  78. QSAR study of anticancer agents: 1,8-Naphthyridine derivatives

    Asian Journal of Chemistry1970journal article

    0 cites

  79. 2-(4-aminophenyl) benzothiazole: A potent and selective pharmacophore with novel mechanistic action towards various tumour cell lines

    Mini-Reviews in Medicinal Chemistry1970journal article

    View DOI
    0 cites

  80. DNA fingerprinting: A prophecy fulfilled

    Pharma Times1970journal article

    0 cites

  81. New spectrophotometric methods applied to the simultaneous determination of diclofenac potassium and tizanidine

    Indian Journal of Pharmaceutical Sciences1970journal article

    0 cites

  82. QSAR analysis of some 5-amino-2-mercapto-1,3,4-thiadiazole based inhibitors of matrix metalloproteinases and bacterial collagenase

    Bioorganic & Medicinal Chemistry Letters1970journal article

    View DOI
    0 cites

  83. QSAR modeling of some 2-methoxy acridones: Cytotoxic in multi drug resistant cells

    International Journal of Cancer Research1970journal article

    0 cites

  84. QSAR studies of 2-aroylindole derivatives: Tubulin inhibitors in cancer therapy

    Asian Journal of Chemistry1970journal article

    0 cites

  85. QSAR studies of anti-malarial agents: 2,4-Diamino pyrimidine derivatives

    Asian Journal of Chemistry1970journal article

    0 cites

  86. Quantitative structure - Activity relationships of selective antagonists of glucagon receptor using QuaSAR descriptors

    Chemical & Pharmaceutical Bulletin1970journal article

    0 cites

  87. Synthesis, biological evaluation and in silico metabolic and toxicity prediction of some flavanone derivatives

    Chemical and Pharmaceutical Bulletin1970journal article

    View DOI
    0 cites

  88. Simultaneous spectrophotometry methods for the estimation of nimesulide and tizanidine in a tablet dosage form

    Indian Journal of Pharmaceutical Sciences1970journal article

    0 cites

  89. QSAR studies and molecular shape analysis of azonafide derivatives as topoisomerase II inhibitors

    Indian Journal of Pharmaceutical Sciences1970journal article

    0 cites